Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1177/0009922810366736 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluating the patient needs and tolerability of Clobazam liquid formulation (Likozam® 1 mg/mL): A French patient and care-givers' centered survey.
Epilepsy Behav
December 2024
Department of Pediatric Neurology, Reference Centre for Rare Epilepsies, Necker Enfants Malades University Hospital, AP-HP, Full Member of EPICARE European Reference Network for Rare and Complex Epilepsies, Université Paris Cité, Paris, France; Dravet Syndrome Alliance France, 3 Sent. Des Larris 45330, Le Malesherbois, France; Imagine Institute, Laboratory of Translational Research for Neurological Disorders, INSERM UMR 1163, Paris, France. Electronic address:
Article Synopsis
- * A survey conducted among caregivers of patients with epilepsy, particularly Dravet syndrome, assessed experiences with different CLB formulations, including aspects like ease of swallowing and adaptability of doses.
- * Out of 87 participants, the majority preferred the liquid form Likozam® for its ease of administration, highlighting its effectiveness for patients aged 2 to 41 years who often underwent polytherapy.
Age-related semiology changes over time.
Epilepsy Behav
December 2024
Mayo Clinic, Department of Neurology, Divisions of Epilepsy and Child and Adolescent Neurology, 200 First Street SW, Rochester, MN 55905, United States.
Article Synopsis
- Understanding seizure semiology across different ages helps identify the origin of seizures in patients with epilepsy.
- In infants, recognizing seizures is difficult due to the immature brain, with common types including epileptic spasms and myoclonic seizures.
- As children grow into preschool and school ages, the types of seizures become more complex and resemble those seen in adults, showing better-defined lateralizing behaviors during focal seizures.
Perampanel reduces seizure frequency in patients with developmental and epileptic encephalopathy for a long term.
Sci Rep
December 2024
Department of Pediatrics, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke City, Tochigi, 329-0498, Japan.
Seizures in patients with developmental and epileptic encephalopathies (DEEs) are often highly resistant to various antiseizure medications. Perampanel (PER) is a novel antiseizure medication that non-competitively inhibits the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor and is expected to reduce seizure frequency not only for focal seizures and generalized tonic-clonic seizures (GTCS) but also for other seizure types. This study aimed to clarify the long-term therapeutic efficacy and tolerability of PER in patients with DEEs.
View Article and Find Full Text PDFCaregiver burden and therapeutic needs in Dravet syndrome - A national UK cross-sectional questionnaire study.
Eur J Paediatr Neurol
November 2024
School of Health and Wellbeing, University of Glasgow, Glasgow, United Kingdom; The Paediatric Neurosciences Research Group, Royal Hospital for Children, Glasgow, United Kingdom. Electronic address:
Background And Objectives: Dravet Syndrome is a severe developmental and epileptic encephalopathy with significant care needs for affected individuals and families. Our objective was to characterise the caregiver burden and therapeutic needs of families caring for an individual with Dravet Syndrome from child to adulthood, to examine age related differences in co-morbidities, and identify current gaps in health and social care.
Methods: Cross-sectional national survey conducted by the patient advocacy group Dravet Syndrome UK (DSUK) emailed to registered families caring for an individual with a confirmed diagnosis of Dravet syndrome.
[Clinical characteristics and genetic analysis of mental retardation disorder with TRIO gene variant].
Zhonghua Er Ke Za Zhi
November 2024
Department of Pediatrics, the Third Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
To summarize the clinical and genetic characteristics of mental retardation disorder (MRD) with TRIO gene variant in children. Case series study. The data of 9 children with TRIO gene variants were collected retrospectively from August 2019 to March 2024 in Department of Neurology, Beijing Children's Hospital, Capital Medical University and Department of Pediatrics, the Third Affiliated Hospital of Zhengzhou University.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!