AI Article Synopsis

  • The study investigates the relationship between ST-segment elevation resolution and high-frequency QRS (HF-QRS) components during thrombolytic therapy in myocardial infarction patients.
  • Three out of twelve patients showed simultaneous resolution of ST elevation and increased HF-QRS after one hour of therapy, indicating potential early correlation.
  • However, as time progressed (2 to 4 hours), the results between standard and high-frequency ECGs became less aligned, suggesting they may provide distinct clinical insights in later stages.

Article Abstract

Background: Resolution of ST-segment elevation in the electrocardiogram (ECG) is used as a reperfusion sign during thrombolytic therapy in acute myocardial infarction. Analysis of high-frequency QRS components (HF-QRS) might provide additional information. The study compares changes in HF-QRS (150-250 Hz) to ST-segment changes in the standard ECG during thrombolytic therapy.

Methods: Twelve patients receiving intravenous thrombolytic therapy were included. A continuous 12-lead ECG recording was acquired for 4 hours.

Results: After 1 hour of therapy, 3 patients showed ST-elevation resolution as well as an increase in HF-QRS. These changes in ST and HF-QRS occurred simultaneously. No other patient showed significant changes in ST or HF-QRS after 1 hour. After 2 and 4 hours, there was less concordance between the standard and high-frequency ECGs.

Conclusions: In patients with early ST-elevation resolution, the standard and high-frequency ECGs show similar results. Later changes are more disparate and may provide different clinical information.

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http://dx.doi.org/10.1016/j.jelectrocard.2010.04.006DOI Listing

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Article Synopsis
  • The study investigates the relationship between ST-segment elevation resolution and high-frequency QRS (HF-QRS) components during thrombolytic therapy in myocardial infarction patients.
  • Three out of twelve patients showed simultaneous resolution of ST elevation and increased HF-QRS after one hour of therapy, indicating potential early correlation.
  • However, as time progressed (2 to 4 hours), the results between standard and high-frequency ECGs became less aligned, suggesting they may provide distinct clinical insights in later stages.
View Article and Find Full Text PDF

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