Neurobiology of sleep.

Clin Chest Med

Department of Medicine, California Pacific Medical Center, 2351 Clay Street, Suite 501, San Francisco, CA 94115, USA.

Published: June 2010

The neurobiology of sleep is introduced in the context of interacting wake and sleep systems. Specifically, the transitions from wake to sleep and from non-rapid eye movement to rapid eye movement sleep are discussed based on the flip-flop switch hypothesis. Regulation of wake and sleep according to the opposing homeostatic and circadian systems are also presented.

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Source
http://dx.doi.org/10.1016/j.ccm.2010.02.004DOI Listing

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