Permanent alopecia following cranial irradiation in a child.

J Cutan Med Surg

Division of Dermatology, Department of Medicine, King Saud Bin Abdulaziz University for Health Sciences, King Abdulaziz Medical City, Riyadh, Saudi Arabia.

Published: October 2010

AI Article Synopsis

  • Cranial irradiation is frequently used to treat childhood leukemia, but it can lead to harmful skin effects, including a rare condition called temporary or permanent hair loss due to scalp fibrosis.
  • The report focuses on a case involving a Saudi boy with acute T-cell lymphoblastic leukemia who developed radiation-induced cicatricial alopecia.
  • Efforts to treat the condition with minoxidil solution were attempted but did not produce positive results.

Article Abstract

Background: Cranial irradiation is commonly used in childhood leukemia, with many potential cutaneous adverse effects. Radiation-induced permanent alopecia owing to scalp fibrosis is a rare but disturbing side effect.

Objective And Conclusion: Here we report a Saudi boy with acute T-cell lymphoblastic leukemia who developed radiation-induced cicatricial alopecia. Topical treatment using minoxidil solution was tried but was ineffective.

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Source
http://dx.doi.org/10.2310/7750.2010.09014DOI Listing

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