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A Rare Case of Coexistence between Epidermoid Cyst and Meningioma in Cerebellopontine Angle Manifesting as Trigeminal Neuralgia.
Neurol India
November 2024
Department of Neurosurgery, Zhongshan Hospital, Fudan University, Shanghai, China.
Neuropathic pain - A clinical primer.
Int Rev Neurobiol
November 2024
Center for Neuroplasticity and Pain (CNAP), Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
Article Synopsis
- Neuropathic pain is categorized as pain resulting from a lesion or disease in the somatosensory nervous system and can have many different diagnoses.
- A detailed patient history, along with standardized questionnaires and pain drawings, helps identify the type of neuropathic pain and accompanying sensory abnormalities, such as allodynia and hyperalgesia.
- Differential diagnosis is crucial, as neuropathic pain can exist alongside other pain types, and additional diagnostic tests may assist in understanding the underlying issues, though the exact relationship between lesions and pain often requires clinical judgment.
Cytoarchitecture and intercellular interactions in the trigeminal ganglion: Associations with neuropathic pain in the orofacial region.
J Oral Biosci
September 2024
Department of Oral Anatomy and Cell Biology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
Article Synopsis
- - Disorders of the trigeminal nerve can lead to significant complications in dental practice, such as neuropathic pain, and understanding the trigeminal ganglion's structure is crucial for managing these issues.
- - The trigeminal ganglion is a complex environment where various cells interact through direct contact or biochemical mediators like ATP and cytokines, which can influence pain responses.
- - Research has highlighted the close proximity of ganglion cells related to different facial areas, suggesting that their interactions may play a role in creating ectopic pain, emphasizing the need for a detailed understanding of these cellular networks.
The effect of microvascular decompression of the CN IX-X root entry/exit zone and the ventrolateral medulla in neurogenic hypertension involving the vertebral/basilar artery.
Front Neurol
June 2024
Department of Neurosurgery, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Introduction: Neurogenic hypertension (HTN) is a type of HTN characterized by increased activity of the sympathetic nervous system. Vascular compression is one of the pathogenic mechanisms of neurogenic HTN. Despite Jannetta's solid anatomical and physiological arguments in favor of neurogenic HTN in the 1970's, the treatment for essential HTN by microvascular decompression (MVD) still lacks established selection criteria.
View Article and Find Full Text PDFNeurological Diseases and Prevalence of Antineuronal Antibodies in Patients with Autoimmune Polyendocrine Syndrome Type 1 - A National Cohort Study.
J Clin Immunol
June 2024
Children's Hospital and Pediatric Research Center, Helsinki University Hospital, Helsinki, Finland.
Article Synopsis
- Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare genetic disease linked to mutations in the autoimmune regulator gene, affecting mainly endocrine organs but also showing autoantibody reactivity to brain structures.
- In a study of 44 Finnish patients with APS-1, 23% were diagnosed with neurological disorders, with migraines, CNS infections, and epilepsy being the most common conditions.
- Serum antineuronal antibodies were found in 42% of 24 tested patients, with GAD65 antibodies being prevalent, indicating a possible connection between APS-1 and neurological issues that require more research.
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