Kendrick Mass Mapping of complex sample compositions, via data derived by Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS) at 1,000,000 resolution, is becoming more common. The Orbitrap mass spectrometer (Fourier Transform Axially Harmonic Orbital Trapping) also uses FT methods and indirect detection, though operating at a maximum resolution of 100,000. We define the more general case of Normalized Mass Mapping to any repeating oligomer unit (e.g., C(3)H(6)O(2)) and apply it to Orbitrap-based mapping of a complex polyglycerol ester, 'green' raw material. Mass measurement errors showed sub-ppm precision and accuracy in many cases, parameters that are critical to obtaining well-defined maps. Map-derived, raw-material-characterization parameters such as iodine value are compared with wet-chemical results and show reasonable agreement for our purposes. The methodology appears applicable to raw material control and eliminates wet chemical methods.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1002/rcm.4526 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Weight Trajectories among Children with Down Syndrome: A Retrospective Chart Review.
J Pediatr
January 2025
Children's Mercy Kansas City, Kansas City, Missouri; University of Missouri-Kansas City, School of Medicine, Kansas City, Missouri; Center for Children's Healthy Lifestyles and Nutrition, Kansas City, Missouri.
Objectives: To evaluate body mass index (BMI) trajectories over time and to evaluate common comorbidities across a large, nationally representative sample of youth with Down syndrome (DS) STUDY DESIGN: This retrospective study included children ages 2 through18 years within the Cerner Health Facts database with a diagnosis of DS and a medical visit between 2010 and 2017. Comorbid conditions were mapped into PheCodes (ie, one or more ICD codes that combine into specific diseases or traits) and were included if they occurred in at least 1% (145 PheCodes) of the sample.
Results: Outcomes trajectories were analyzed through generalized additive mixed models.
Biomechanical mechanisms for modulating stride frequency in walking.
J Biomech
January 2025
Department of Kinesiology, University of Massachusetts Amherst, Amherst, MA, United States; School of Kinesiology, University of Michigan, Ann Arbor, MI, United States.
Humans typically choose to walk at a self-selected stride frequency that minimizes their metabolic cost. However, when environmental constraints are present (e.g.
View Article and Find Full Text PDFMultilayer Composite Electrodes for Simultaneously Improved Mechanical and Electrochemical Performance.
ACS Appl Mater Interfaces
January 2025
The Harold & Inge Marcus Department of Industrial & Manufacturing Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, United States.
Structural batteries offer a transformative approach to integrate energy storage directly into the frameworks of electric vehicles and aircrafts, enabling multifunctional construction. This study presents a nacre-inspired multilayer composite electrode fabricated via the cold sintering process (CSP), achieving a balance of enhanced electrochemical performance and mechanical robustness. The composite electrode combines active electrode materials with a ductile conducting polymer-carbon-mixture phase in a layered architecture.
View Article and Find Full Text PDFShrinking the lymphatic filariasis map of Zimbabwe: Reassessing the population requiring treatment through confirmatory mapping.
Int J Infect Dis
January 2025
Kenya Medical Research Institute, Nairobi, Kenya.
Objectives: Zimbabwe is endemic for lymphatic filariasis (LF) with 39 districts identified for mass drug administration (MDA) in 2014. The objective of this study was to reassess the current population requiring MDA.
Methods: The LF confirmatory mapping method was used to evaluate the prevalence of circulating filarial antigens (CFA) among school-aged children (9-14 years) in previously endemic districts.
Functional epitope mapping of cell surface glucose-regulated protein 94: A combinatorial approach for therapeutic targeting.
Int J Biol Macromol
January 2025
Department of Chemistry, Kookmin University, Seoul 02707, Republic of Korea; Department of Biopharmaceutical Chemistry, Kookmin University, Seoul 02707, Republic of Korea; Antibody Research Institute, Kookmin University, Seoul 02707, Republic of Korea. Electronic address:
Glucose-regulated protein 94 (GRP94) overexpression plays a critical role in tumor cell survival across various cancers. Previously, we developed K101.1, a fully human antibody targeting cell surface GRP94, which effectively inhibits tumor angiogenesis in colorectal cancer (CRC).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!