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Spinal block with 10 mg of hyperbaric bupivacaine associated with 5 microg of sufentanil for cesarean section. Study of different volumes. | LitMetric

AI Article Synopsis

  • - The study aimed to analyze how different volumes of a spinal anesthetic (4 mL vs. 3 mL) containing hyperbaric bupivacaine and sufentanil affect anesthesia during elective cesarean sections, given the physiological changes in pregnant patients.
  • - Forty patients were split into two groups based on anesthetic volume, and various parameters like onset time, sensory and motor effects, and duration of pain relief were monitored.
  • - Results indicated that the 4 mL group had significantly longer pain relief compared to the 3 mL group, while side effects remained similar across both, with no adverse effects noted for mothers or babies.

Article Abstract

Background And Objectives: Several factors affect the cephalad dispersion of the anesthetic solution in the subarachnoid space; among them, physiological changes of pregnancy and the dose and volume of the local anesthetics should be mentioned. The objective of this study was to assess the effectivity and side effects of different volumes of the subarachnoid administration of the association of hyperbaric bupivacaine and sufentanil in cesarean sections.

Methods: Forty patients, ASA I and II, undergoing elective cesarean section under spinal block were divided in two groups, according to the volume of the anesthetic solution: Group I (4 mL) and Group II (3 mL). The association of hyperbaric bupivacaine (10 mg(2) mL) and sufentanil (5 microg-1 mL) was used in both groups. In Group I, 1 mL of NS was added to the solution to achieve the volume of 4 mL. The following parameters were evaluated: latency of the blockade; upper limit of the sensorial blockade; degree of motor blockade; time for regression of the motor blockade; total duration of analgesia; maternal side effects; and neonatal repercussions.

Results: Latency, the upper limit of the sensorial blockade, and the degree and time for regression of the motor blockade were similar in both groups; duration of analgesia was greater in Group I than in Group II, which was statistically significant. The incidence of side effects was similar in both groups. Maternal cardiocirculatory changes and neonatal repercussions were not observed.

Conclusions: Four milliliter of anesthetic solution composed of hyperbaric bupivacaine, 10 mg, associated with 5 microg of sufentanil was more effective than 3 ml of the same solution, providing better intra-and postoperative analgesia without maternal-fetal repercussions.

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Source
http://dx.doi.org/10.1016/s0034-7094(10)70016-7DOI Listing

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