The total synthesis of (3R,5R)-harzialactone A (1) and its (3R,5S)-isomer (2) is described. Epoxide opening with thioacetal and diastereoselective reductions are used as key reactions.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871370 | PMC |
| http://dx.doi.org/10.3762/bjoc.6.8 | DOI Listing |
Publication Analysis
Top Keywords
synthesis 3r5r-harzialactone
8
3r5r-harzialactone 3r5s-isomer
8
3r5s-isomer total
4
total synthesis
4
3r5s-isomer described
4
described epoxide
4
epoxide opening
4
opening thioacetal
4
thioacetal diastereoselective
4
diastereoselective reductions
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!