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Complicated Long Term Vaccine Induced Thrombotic Immune Thrombocytopenia-A Case Report.
Vaccines (Basel)
November 2021
Department for Transfusion Medicine, Institute for Immunology and Transfusion Medicine, University Medicine Greifswald, 17487 Greifswald, Germany.
Background And Objectives: Vaccine induced thrombotic thrombocytopenia (VITT) may occur after COVID-19 vaccination with recombinant adenoviral vector-based vaccines. VITT can present as cerebral sinus and venous thrombosis (CSVT), often complicated by intracranial hemorrhage. Today it is unclear, how long symptomatic VITT can persist.
View Article and Find Full Text PDFClinical, Laboratory Features and Clinical Courses of Patients with Wiskott Aldrich Syndrome and X-linked Thrombocytopenia-A single center study.
Immunol Invest
July 2022
Institute of Child Health, Division of Immunology, Hacettepe University Medical School, Ankara, Turkey.
Objective: Wiskott Aldrich Syndrome is an X-linked primary immunodeficiency disorder characterized by microthrombocytopenia, severe immunodeficiency, and eczema. To define clinical-laboratory features, genetic defects (known/novel) of 23 patients of Wiskott Aldrich Syndrome/X-linked Thrombocytopenia (WAS/XLT) cohort, establish relationships between molecular defects and clinical features if present, evaluate patients who underwent hematopoietic stem cell transplantation (HSCT) and did not.
Methods: Qualitative analysis from patients' hospital files and Sanger sequencing for molecular diagnosis was performed.
Immune Thrombocytopenia-A Disease or a Group of Disorders? Where Do We Stand in 2019?
Hamostaseologie
August 2019
Center for Clinical Transfusion Medicine, University Hospital of Tübingen, Tübingen, Germany.
Asymptomatic thrombocytopenia developing during pregnancy (gestational thrombocytopenia)--a clinical study.
Q J Med
August 1992
Derriford Hospital, Plymouth, Devon.
During pregnancy some women develop unexplained thrombocytopenia (gestational thrombocytopenia). Previous studies have detected abnormal platelet antibodies, suggesting an autoimmune aetiology. To determine whether gestational thrombocytopenia is associated with increased maternal bleeding or adversely affects the fetus, 31 pregnant women with asymptomatic thrombocytopenia were compared with 12 women with thrombocytopenia associated with pre-eclampsia and 34 normal pregnant controls.
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