Facial epidermal inclusion cysts are associated with smoking in men: a hospital-based case-control study.

Dermatol Surg

Department of Dermatology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.

Published: June 2010

AI Article Synopsis

  • Epidermal inclusion cysts (EICs) are common skin growths in adults, and there’s a suggestion that smoking might be a risk factor for their development.
  • A study analyzed 301 patients with EICs and compared them to a control group, finding that male patients with facial EICs were more likely to be smokers than those in the control group.
  • The results suggest a potential link between smoking and the occurrence of EICs, particularly in men.

Article Abstract

Background: Epidermal inclusion cysts (EICs) are a common cutaneous disorder in adults. The etiology of EICs remains obscure. Our clinical experience suggests that smoking may be a risk factor for the development of EICs. OBJECTIVE To determine whether the number and sites of EICs are related to smoking behavior and quantity.

Methods And Materials: We retrospectively surveyed patients pathologically diagnosed with EICs at our hospital. A control group comprised patients who underwent surgical procedures for diagnoses other than EICs. Smoking history was obtained through telephone or clinical interviews.

Results: Three hundred one patients with EICs were identified in our archives: 217 men (mean age 37.1, range 9-77) and 84 women (mean age 41.3, range 9-82). Detailed medical records and smoking history were available for 225 patients. Two hundred twenty-five age- and sex-matched patients were enrolled in the control group. Results showed that a higher percentage of men with facial EICs than of control subjects were smokers (p<.01). No such association was found in women with EICs.

Conclusion: Smoking may contribute to the development of EICs.

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Source
http://dx.doi.org/10.1111/j.1524-4725.2010.01565.xDOI Listing

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