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Digital detector PET/CT increases Centiloid measures of amyloid in Alzheimer's disease: A head-to-head comparison of cameras.
J Alzheimers Dis
January 2025
Health and Biosecurity, Commonwealth Scientific and Industrial Research Organisation, Brisbane, QLD, Australia.
Background: The introduction of therapeutics for Alzheimer's disease has led to increased interest in precisely quantifying amyloid-β (Aβ) burden for diagnosis, treatment monitoring, and further clinical research. Recent positron emission tomography (PET) hardware innovations including digital detectors have led to superior resolution and sensitivity, improving quantitative accuracy. However, the effect of PET scanner on Centiloid remains relatively unexplored and is assumed to be minimized by harmonizing PET resolutions.
View Article and Find Full Text PDFEach hour injures, the last one kills.
Australas Psychiatry
January 2025
Crawford School of Public Policy, The Australian National University, Canberra, ACT, Australia.
The haemorrhage of psychiatrists from the NSW state-funded mental health system parallels losses throughout Australia, and internationally. The lack of workforce cripples the capacity to provide adequate care. There has been persistently neglectful under-resourcing of the care of people with severe mental illness.
View Article and Find Full Text PDFThe safety and efficacy of cannabinoids for the treatment of mental health and substance use disorders: protocol for a systematic review and meta-analysis.
Syst Rev
January 2025
The Matilda Centre for Research in Mental Health and Substance Use, Level 6 Jane Foss Russell Building, The University of Sydney, Camperdown, NSW, 2006, Australia.
There has been a global increase in the use of cannabinoids as a treatment for mental health (MH) and substance use disorders (SUD). In 2016, an Australian government-funded review found that although medicinal cannabinoids accounted for a small reduction in MH symptoms, the results varied according to study design. There has since been a rise in randomised controlled trials (RCTs) aiming to examine the efficacy of cannabinoids for the treatment of MH and SUD.
View Article and Find Full Text PDFSystematic review and meta-analysis of family-based interventions for early psychosis: Carer and patient outcomes.
Schizophr Res
January 2025
Healthy Brain and Mind Research Centre, School of Behavioural and Health Sciences, Australian Catholic University, Fitzroy, VIC, Australia; Department of Psychiatry, University of North Carolina, Chapel Hill, NC, United States of America.
Background: Previous reviews have indicated that family interventions in early psychosis are beneficial for patients and family caregivers. Given recent developments in research and service provision an updated review is warranted.
Methods: We conducted a systematic review and meta-analysis of family intervention trials in the first 5 years after psychosis onset.
Mapping the regional and remote specialised mental health workforce: Commentary on the AIHW data for 2022-2023.
Australas Psychiatry
January 2025
Consortium of Australian-Academic Psychiatrists for Independent Policy and Research Analysis (CAPIPRA), Canberra, ACT, Australia.
Objective: The Australian Institute of Health and Welfare publishes statistical indicator reports on the specialised mental health workforce. These include data for 2022-2023 on psychiatrists, mental health nurses, mental health occupational therapists, psychologists and mental health social workers. We provide a brief commentary on these reports, reflecting upon the implications of such changes for psychiatric practice and patient care.
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