Influence of copper ions on white blood cells parameters in Carassius auratus gibelio was investigated. Changes in cytogenetic parameters and instability in erythrocytes and epithelial cells of gills were estimated in reply to influence of copper solutions. The frequency of epithelial gill cells at a stage of apoptosis was investigated. The opportunity to use the hematological parameters and cytogenetic instability set for xenobiotics effects in fishes was shown.

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