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Plasma cell-free DNA assay: a diagnostic tool for tuberculosis lymphadenitis.
Infect Dis (Lond)
March 2025
Armauer Hansen Research Institute, Addis Ababa, Ethiopia.
Background: Bacterial confirmation in suspected tuberculosis lymphadenitis patients is challenging. This study evaluates plasma cell-free DNA as a diagnostic tool for tuberculosis lymphadenitis.
Methods: A quantitative PCR assay targeting IS, IS, and genes was performed on plasma samples.
Characterization of the Temporal Dynamics of the Endothelial-Mesenchymal-like Transition Induced by Soluble Factors from Dengue Virus Infection in Microvascular Endothelial Cells.
Int J Mol Sci
February 2025
Grupo Medicina de Translación-Facultad de Medicina, Universidad de Antioquia, Medellín 050010, Colombia.
Dengue virus (DV) infection poses a severe life-threatening risk in certain cases. This is mainly due to endothelial dysregulation, which causes plasma leakage and hemorrhage. However, the etiology of DV-induced endothelial dysregulation remains incompletely understood.
View Article and Find Full Text PDFClinical significance and pathogenesis of GBP5 in infectious mononucleosis associated liver injury.
Ital J Pediatr
March 2025
Department of Infectious Diseases, Children's Hospital of Soochow University, Suzhou, 215000, China.
Background: Infectious mononucleosis (IM) is a common disease in children; however, liver injury is its most common complication. However, the pathogenesis of IM complicated with liver injury is ambiguous. Thus, this study aimed to explore the potential mechanism of IM-associated liver injury.
View Article and Find Full Text PDFHypoxemia exerts detrimental effects on the choroid plexuses and cerebrospinal fluid system in rats.
Fluids Barriers CNS
March 2025
Department of Physiology, College of Medicine, Kuwait University, P.O. Box 24923, 13110, Safat, Kuwait.
Background: Hypoxemia can cause secondary acute brain injury, but the mechanisms behind it are not entirely clear and could involve disturbances in the brain extracellular fluids. We aimed to explore the effects of hypoxemia on the choroid plexus (CPs) and cerebrospinal fluid (CSF) system in rats.
Methods: Male Sprague Dawley rats were kept in O control in vivo cabinet with either 21% (normoxia) or 8% O (hypoxemia) for up to 48 h.
Spleen Involvement at Diagnosis of Multiple Myeloma: A Case Report and Literature Review.
Cancer Rep (Hoboken)
March 2025
UOC Haematology, ASL Viterbo-Santa Rosa Hospital, Viterbo, Italy.
Background: Multiple myeloma (MM) is more often characterized by clonal plasma cell proliferation restricted to the bone marrow. However, a small percentage of patients with MM develop extramedullary disease (EMD): this type of localization is found in 1.7%-4.
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