Internal model-based control (IMC) has been shown to possess many advantages over PID control, particularly in the presence of significant process deadtime. Implementation of IMC is simplified in a large class of industrial applications where the process dynamics can be adequately characterized by a simple first-order model requiring only estimates of process gain, lag time constant, and deadtime for implementing the controller design. Tuning of the controller is easily and intuitively done by adjusting the filter time constant; decreasing the time constant speeds up the closed-loop response, and increasing it yields generally a slower but more stable response. There are problems, however, in applying the IMC approach to an integrating process, i.e., a process with a pole at the origin. First, for a first-order lag filter, the steady-state error due to a process input disturbance is generally non-zero. This error can be reduced to zero with a higher-order lead lag filter with proper choice of filter parameters. This is at a cost, however, of increased design complexity, amplification of noise in the controller signals, and a potential numerical overflow issue due to an integrator within the IMC computation loop. To overcome these problems, an alternative IMC implementation is proposed where the integrator in the model is approximated by a first-order lag with a very large time constant. It is shown analytically and verified by computer simulation that this approach assures zero steady-state error for setpoint (SP) changes and process disturbance inputs. Computer simulation studies also show that the transient response can be satisfactorily tuned by proper choice of the filter time constant and that potential numerical instability issues are essentially eliminated. Further, since the choice of time constant in the lag used to approximate the integrator function in the modified IMC also affects the PV(t) response approach, another degree of freedom in the tuning process is introduced. This modified IMC approach has been used successfully in several real-world applications.
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http://dx.doi.org/10.1016/j.isatra.2010.03.012 | DOI Listing |
Trials
January 2025
Department of Anesthesiology and Pain Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Korea.
Background: Prophylactic parenteral administration of antibiotics is strongly recommended to prevent surgical site infection (SSI). Cefoxitin is mainly administered intravenously in colorectal surgery. The current standard method for administering prophylactic antibiotics in adults is to administer a fixed dose quickly before skin incision.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Subject-specific parameters in lumped hemodynamic models of the cardiovascular system can be estimated using data from experimental measurements, but the parameter estimation may be hampered by the variability in the input data. In this study, we investigate the influence of inter-sequence, intra-observer, and inter-observer variability in input parameters on estimation of subject-specific model parameters using a previously developed approach for model-based analysis of data from 4D Flow MRI acquisitions and cuff pressure measurements. The investigated parameters describe left ventricular time-varying elastance and aortic compliance.
View Article and Find Full Text PDFWater Res
December 2024
Institute for Advanced Membrane Technology (IAMT), Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344 Eggenstein-Leopoldshafen, Germany. Electronic address:
In flow-through reactors, the photodegradation rate can be improved by enhancing contact and increasing the photocatalyst loading. Both can be attained with a higher surface-to-volume ratio. While previous studies focused on thin membranes (30 - 130 µm) with small pore sizes of 20 - 650 nm, this work employed poly(tetrafluoroethylene) (PTFE) supports, of which pore sizes are in the order of 10 µm, while the porosities and thicknesses are variable (22.
View Article and Find Full Text PDFClin Orthop Relat Res
January 2025
Department of Orthopaedic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Background: A variety of clinically important benchmarks of success (CIBS) have been defined for total shoulder arthroplasty (TSA) to quantify success. However, it is unclear how the preoperative status of the patient influences their likelihood of achieving each CIBS.
Questions/purposes: (1) What proportion of patients achieve commonly used CIBS after TSA? (2) Is there a relationship between a patients' preoperative function and their probability of achieving different CIBS? (3) Does there exist preoperative ranges for each outcome measure that are associated with greater achievement of CIBS?
Methods: We retrospectively queried a multicenter shoulder arthroplasty database for primary anatomic TSA (aTSA) and reverse TSA (rTSA).
Chemphyschem
January 2025
Universität des Saarlandes, Biophysikalische Chemie FR 8.1 Chemie, Campus B 2 2, 66123, Saarbrücken, GERMANY.
The reaction of terrylene in p-terphenyl with molecular oxygen is reinvestigated by TIRF-microscopy with λexc = 488 nm or λexc = 561 nm and 488 nm. A similar range of fluorescent products is obtained under both experimental conditions with a reaction quantum yield Φr > 10-7 for those molecules which undergo the photoreaction. The majority of these oxygen-susceptible molecules reacts via an electronically relaxed, dark intermediate, presumably an endoperoxide, with a lifetime of
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