Time course of lipid peroxidation and the state of antioxidant system of patients with chronic kidney disease were studied. Increases of conjugated dienes, malonic dialdehyde, lipid peroxidation degree were found. Alterations in ceruloplasmin activity, observed in blood of patients depended on the stage of the disease. Content of lipid peroxidation products was also dissimilar during the first and the second stage of disease. Estimation of ceruloplasmin activity and content of conjugated dienes were the most suitable parameters for monitoring treatment of chronic renal disease.
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