The authors describe an innovative adolescent evening clinic at the REACH Centre, staffed by nurses and counsellors with family physician consultation available as required.
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J Funct Morphol Kinesiol
January 2025
Institute of Human Movement Science, Sport and Health, University of Graz, 8010 Graz, Austria.
: Increasing exercise intensity and performance output with superimposed vibration gains interest, especially in high-performance training. However, the additional benefit of vibration in passive stretching exercises and its mechanisms remain unclarified. : Passive stretching with (ST+V) and without (ST) vibration (20 Hz) was performed in male Olympic youth skiing athletes ( = 8, age: 17.
View Article and Find Full Text PDFFront Endocrinol (Lausanne)
January 2025
Department of Endocrinology, Genetics and Metabolism, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) has become one of the most prevalent chronic liver diseases worldwide. The serum uric acid-to-high-density lipoprotein cholesterol ratio (UHR) has been recognized as a novel marker for metabolic diseases, including MASLD. However, all previous studies were performed in adults.
View Article and Find Full Text PDFBackground: Prior to the introduction of disease-modifying treatments (DMTs), children with type 1 spinal muscular atrophy (SMA) typically did not survive beyond the age of 2 years; management was mainly palliative. Novel therapies have made this a treatable condition, resulting in increased life expectancy and more time spent upright. Survival and improved function mean spinal asymmetry is a new complication with limited data on its prevalence and severity and no current guidelines on management and treatment.
View Article and Find Full Text PDFHum Pathol
January 2025
Département de Biopathologie CHRU-ICL, CHRU Nancy, Vandoeuvre-lès-Nancy, France; INSERM, U1256, NGERE - University of Lorraine, Vandoeuvre-lès-Nancy, France. Electronic address:
Neuroblastoma is a common childhood tumor originating from neural crest progenitors with variable clinical behavior. Despite improved overall survival, factors such as stage, histoprognosis, MYCN status, and age still influence outcome. MCM6 regulates DNA replication and contributes to cancer progression.
View Article and Find Full Text PDFJMIR Ment Health
January 2025
School of Applied Psychology & Centre for Mental Health, Griffith University, Mt Gravatt, Australia.
Background: Self-guided internet-delivered cognitive behavioral therapy (ICBT) achieves greater reach than ICBT delivered with therapist guidance, but demonstrates poorer engagement and fewer clinical benefits. Alternative models of care are required that promote engagement and are effective, accessible, and scalable.
Objective: This randomized trial evaluated whether a stepped care approach to ICBT using therapist guidance via videoconferencing for the step-up component (ICBT-SC[VC]) is noninferior to ICBT with full therapist delivery by videoconferencing (ICBT-TG[VC]) for child and adolescent anxiety.
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