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Real-time monitoring by interferometric light microscopy of phage suspensions for personalised phage therapy.
Sci Rep
December 2024
Pharmacy Department, Hospices Civils de Lyon, Hôpital E. Herriot, Plateforme FRIPHARM, 69437, Lyon, France.
Phage therapy uses viruses (phages) against antibiotic resistance. Tailoring treatments to specific patient strains requires stocks of various highly concentrated purified phages. It, therefore, faces challenges: titration duration and specificity to a phage/bacteria couple; purification affecting stability; and highly concentrated suspensions tending to aggregate.
View Article and Find Full Text PDFIn situ visualization of interfacial processes at nanoscale in non-alkaline Zn-air batteries.
Nat Commun
December 2024
Key Laboratory of Molecular Nanostructure and Nanotechnology, Beijing National Laboratory for Molecular Sciences, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing, China.
Zn-air batteries (ZABs) present high energy density and high safety but suffer from low oxygen reaction reversibility and dendrite growth at Zn electrode in alkaline electrolytes. Non-alkaline electrolytes have been considered recently for improving the interfacial processes in ZABs. However, the dynamic evolution and reaction mechanisms regulated by electrolytes at both the positive and Zn negative electrodes remain elusive.
View Article and Find Full Text PDFLaser scribed proton exchange membranes for enhanced fuel cell performance and stability.
Nat Commun
December 2024
Department of Chemical Engineering, Electrochemical Innovation Lab, University College London, London, UK.
High-temperature proton exchange membrane fuel cells (HT-PEMFCs) offer solutions to challenges intrinsic to low-temperature PEMFCs, such as complex water management, fuel inflexibility, and thermal integration. However, they are hindered by phosphoric acid (PA) leaching and catalyst migration, which destabilize the critical three-phase interface within the membrane electrode assembly (MEA). This study presents an innovative approach to enhance HT-PEMFC performance through membrane modification using picosecond laser scribing, which optimises the three-phase interface by forming a graphene-like structure that mitigates PA leaching.
View Article and Find Full Text PDFFrom Traditional to Cutting-Edge: Transforming Pulmonary Valve Assessment With Advanced Echocardiography Techniques.
Echocardiography
January 2025
Department of Cardiology, German Heart Center Charité, Berlin, Germany.
The pulmonary valve (PV), although often less emphasized than other heart valves, is crucial for cardiac function and hemodynamics. Historically, the PV has been underrepresented in echocardiographic assessments due to its rare involvement in pathological conditions, particularly in adults. Additionally, the anatomical position of the PV makes it one of the most challenging valves to visualize using conventional echocardiography.
View Article and Find Full Text PDFNavigating the Dynamic Nature of Mitral Regurgitation With the Use of Multimodality Imaging in a Young Woman.
Cureus
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Cardiology, Mount Sinai West Hospital, New York, USA.
The mechanism and severity of mitral valve (MV) regurgitation (MR) play a critical role in guiding treatment decisions. Transthoracic echocardiography (TTE) is the primary diagnostic modality for evaluating MV disease. Discordant findings on TTE can be further quantified through transesophageal echocardiography (TEE).
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