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Acute pancreatitis in children in Japan is often caused by an anatomical abnormality of the pancreatic and bile duct, resulting in fever, abdominal pain, vomiting, diarrhea, and other symptoms. Crohn's disease, however, is a chronic granulomatous inflammatory bowel disease with ulcerative lesions of the intestinal tract of unknown cause that occurs mainly in young people, with symptoms similar to those of acute pancreatitis. We report a case of acute pancreatitis diagnosed in a patient not only with incomplete fusion of the pancreatic duct but also with Crohn's disease.

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PANCREATODUODENECTOMY AS TREATMENT FOR RECURRENT ACUTE PANCREATITIS DUE TO PANCREAS DIVISUM.

Arq Bras Cir Dig

December 2024

From Universidade Federal do Maranhão, Hospital Universitário Presidente Dutra, Department of Gastrointestinal Surgery, Hepatopancreatobiliary and Liver Transplant Unit - São Luis (MA), Brazil.

Background: Pancreas divisum is an anatomical abnormality where the junction of the main and accessory pancreatic duct fails to occur and the smaller-caliber duct acts as dominant, resulting in overload during the drainage of the organ's secretion through the minor duodenal papilla.

Aims: To report a case of recurrent acute pancreatitis due to symptomatic pancreas divisum who underwent pancreatoduodenectomy.

Case Report: A 21-year-old male patient presented with intermittent painful crises, located in the upper abdomen, with radiation to the back, associated with nausea and vomiting, for the past three years.

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Endoscopic Retrograde Cholangiopancreatography: Pancreatic Endoscopy.

Gastroenterol Clin North Am

December 2024

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA. Electronic address:

Article Synopsis
  • - The role of pancreatic endoscopic retrograde cholangiopancreatography (ERCP) has shifted from primarily diagnosing issues to being mainly used for therapeutic treatments, especially for conditions like pancreatitis.
  • - ERCP is particularly effective in treating pancreatic duct (PD) problems, such as leaks, disruptions, strictures, and stone removals.
  • - Advances in pancreatoscopy enhance ERCP's effectiveness by enabling precise treatment of conditions and aiding in the identification and surgical planning for pancreatic tumors.
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Article Synopsis
  • Pancreas divisum (PD) is a common birth defect of the pancreas, but the genetic factors behind it are still unclear, prompting a genome-wide study to find potential genetic links.
  • Researchers analyzed data from 13,940 participants, identifying a significant genetic locus on chromosome 3q29 associated with PD, specifically linked to two genes related to cellular functions.
  • The study not only established a genetic link to PD but also identified potential regulatory genes that might influence pancreatic development, which could aid in better understanding and treating related pancreatic conditions.
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