Herpes viruses in transplant recipients: HSV, VZV, human herpes viruses, and EBV.

Infect Dis Clin North Am

Division of Infectious Diseases, Hospital of the University of Pennsylvania, 3rd Floor Silverstein Pavilion, Suite E, 3400 Spruce Street, Philadelphia, PA 19104, USA.

Published: June 2010

The herpes viruses are responsible for a wide range of diseases in patients following transplant, resulting from direct viral effects and indirect effects, including tumor promotion. Effective treatments and prophylaxis exist for the neurotropic herpes viruses HSV-1, HSV-2, varicella zoster virus, and possibly HHV-6. Antivirals seem to be less effective at prevention of the tumor-promoting effects of Epstein-Barr virus and HHV-8. Reduction in immunosuppression is the cornerstone to treatment of many diseases associated with herpes virus infections.

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http://dx.doi.org/10.1016/j.idc.2010.01.003DOI Listing

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