To reveal preclinical cardiac performance changes, conventional and unique ECG processing procedures were used in 101 individuals. A classification of heart function was developed, which was based on a comprehensive assessment of ECG. The results of the clinicofunctional classification were well comparable with those of a quantitative ECG analysis made with heuristical methods. The ratios of various ECG parameters are more informative than the absolute values of these parameters. In screening, the quantitative ECG analysis have some advantages over the visual one as it requires no thorough clinicopharmacological study. The symmetrical approach to an ECG analysis with the use of geometrical methods of simulation may be useful for the criterion assessment of preclinical alteration in cardiac performance.
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J Electrocardiol
January 2025
Department of Cardiology, University Hospitals of Leicester NHS Trust, Glenfield Hospital, Leicester, UK; Department of Cardiovascular Sciences, Clinical Science Wing, University of Leicester, Glenfield Hospital, Leicester, UK; National Institute for Health Research Leicester Research Biomedical Centre, Leicester, UK.
Background: Pulmonary vein isolation (PVI) for paroxysmal atrial fibrillation (PAF) can be performed using one-shot cryoballoon ablation (cryo) or point-by-point radiofrequency ablation (RF). This study compares the changes in P-wave parameters between both ablation methods.
Methods: This single-centre retrospective study included contact force RF and second-generation cryo for PAF between 2018 and 2019.
Comput Biol Med
January 2025
Department of Automation, Tsinghua University, Beijing, China. Electronic address:
Background: Prognosis prediction in the intensive care unit (ICU) traditionally relied on physiological scoring systems based on clinical indicators at admission. Electrocardiogram (ECG) provides easily accessible information, with heart rate variability (HRV) derived from ECG showing prognostic value. However, few studies have conducted a comprehensive analysis of HRV-based prognostic model against established standards, which limits the application of HRV's prognostic value in clinical settings.
View Article and Find Full Text PDFFront Neurol
December 2024
Center for Data Science, Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, GA, United States.
Background: Traumatic brain injury (TBI) disrupts normal brain tissue and functions, leading to high mortality and disability. Severe TBI (sTBI) causes prolonged cognitive, functional, and multi-organ dysfunction. Dysfunction of the autonomic nervous system (ANS) after sTBI can induce abnormalities in multiple organ systems, contributing to cardiovascular dysregulation and increased mortality.
View Article and Find Full Text PDFJ Physiol
January 2025
Department of Biological Sciences, Southern Methodist University, Dallas, TX, USA.
Sudden unexpected death in epilepsy (SUDEP) is a devastating complication of epilepsy with possible sex-specific risk factors, although the exact relationship between sex and SUDEP remains unclear. To investigate this, we studied Kcna1 knockout (Kcna1) mice, which lack voltage-gated Kv1.1 channel subunits and are widely used as a SUDEP model that mirrors key features in humans.
View Article and Find Full Text PDFSleep Breath
January 2025
Departments of Otolaryngology, Kangwon National University College of Medicine, Kangwon National University Hospital, 156, Baengnyeong-ro, Chuncheon-Si, Gangwon-Do, Chuncheon, 24289, Republic of Korea.
Purpose: The effect of allergic rhinitis (AR) on autonomic nervous system in patients with obstructive sleep apnea (OSA) remains unclear. We utilized heart rate variability (HRV) analysis to assess cardiac autonomic activity in patients with OSA, comparing those with and without allergic rhinitis (AR).
Methods: We enrolled 182 patients who visited our sleep clinic complaining of habitual snoring or apnea during sleep.
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