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Asymmetric Michael addition of aldehydes to nitroalkenes using a primary amino acid lithium salt. | LitMetric

Asymmetric Michael addition of aldehydes to nitroalkenes using a primary amino acid lithium salt.

Org Biomol Chem

Division of Chemical Process Engineering, Graduate School of Engineering, Hokkaido University, 8, Kita 13-jo Nishi, Kita-ku, 060-8628, Sapporo, Japan.

Published: June 2010

Enantioselective Michael addition of aldehydes to nitroalkenes was successfully carried out by asymmetric catalysis with L-phenylalanine lithium salt, giving gamma-nitroaldehydes in good yields with high enantioselectivity.

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Source
http://dx.doi.org/10.1039/c003940cDOI Listing

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