Candida parapsilosis spondylodiscitis after lumbar discectomy.

J Korean Neurosurg Soc

Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Published: April 2010

AI Article Synopsis

  • Candida is a rare cause of spinal infections, particularly in patients with weakened immune systems, as illustrated by a case involving a 70-year-old woman who developed spondylodiscitis after lumbar surgery.
  • Imaging revealed an infection at the L5-S1 intervertebral space, leading to surgery where infected material was removed, and tests confirmed the presence of Candida parapsilosis.
  • Post-surgery, the patient underwent a thorough treatment regimen with fluconazole and made a full recovery within six months, highlighting the importance of prompt diagnosis and treatment for such infections.

Article Abstract

Candida is a relatively rare cause of spinal infections that commonly affects immunocompromised patients. A 70-year-old woman, who underwent a lumbar discectomy on L5-S1 two months earlier, was admitted to our department complaining of persistent back and leg pain. Magnetic resonance imaging showed irregular enhancing mass lesion in L5-S1 intervertebral space, suggest of pyogenic discitis with epidural abscess. The surgery was performed via retroperitoneal approach and the infected material at L5-S1 intervertebral space was removed. The histological examination of the specimen revealed chronic inflammation involving the bone and soft tissue, and a culture of the excised material was positive for Candida parapsilosis. The patient received intravenous fluconazole for 4 weeks after surgery and oral fluconazole 400 mg/day for 3 months after surgery. The patient made a full recovery with no symptoms 6 months after surgery. We present a rare case of spondylodiscitis after a lumbar discectomy due to Candida parapsilosis and discuss treatment option with a review of the literatures.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864824PMC
http://dx.doi.org/10.3340/jkns.2010.47.4.295DOI Listing

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