Thermography (TG) is used as a contact free method for investigation of the myocardium ischemic injury. In coronary bypass surgery without artificial blood circulation it is important to know how cessation of blood supply affects the myocardium. In experiments on working heart, TG allows monitoring temperature at the desired point of the epicardium. The aim was to investigate relations between myocardial ischemia and temperature and to prove that the ischemic tissue and border zones can be determined by TG. Experiments were performed on mongrel dogs. In the areas of induced ischemia, ventricular surface thermograms (T) and electrograms (EG) were recorded. The obtained data showed that temperatures in ischemic area and border zone of myocardium were different from those in healthy myocardium. A detailed analysis of T of ischemic area showed that between ischemic and healthy myocardium a border zone is formed which is very important for arrhythmia genesis. The border zone is several millimeters wide, and its temperature is 1C higher than in healthy myocardium. The curve of the dynamics of temperature measured at all points of the ischemic zone has been created. Correlation between myocardium temperatures and characteristics of EG of ischemic zones is shown. Conclusion. The data show that TG is an appropriate method for determination of ischemic area and border zone in ventricular myocardium. TG gives a possibility to evaluate functional status of myocardium in a contact free way and may be applied for determination of ischemic damage of myocardium during cardiosurgery.
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Int J Mol Sci
January 2025
Department of Cell Biology, IFOM ETS-The AIRC Institute of Molecular Oncology, Via Adamello, 16, 20139 Milan, Italy.
The regeneration of endothelial cells (ECs) lining arteries, veins, and large lymphatic vessels plays an important role in vascular pathology. To understand the mechanisms of atherogenesis, it is important to determine what happens during endothelial regeneration. A comparison of these processes in the above-mentioned vessels reveals both similarities and some significant differences.
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Department of Ophthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, United States.
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Thermal and Energetic Systems Studies Laboratory (LESTE), LR99ES31, College of Engineering, University of Monastir, 5000, Monastir, Tunisia.
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Department of Cardiology, Zhongda Hospital, School of Medicine, Southeast University, 87 Dingjiaqiao, Nanjing 210009, China. Electronic address:
Treatment of myocardial ischemia-reperfusion (MI/R) injury still faces the lack of clinically approved drugs. Apelin-13 is a highly promising drug candidate of MI/R injury, but hampered by its extremely short half-life in plasma. This calls for efficient and smart delivering system for Apelin-13 delivery, but has not been reported.
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Division of Neuropathology and Neurochemistry, Department of Neurology, Medical University Vienna, Vienna, Austria.
Just 40 years ago, Europe was divided into the Eastern communist bloc, which included the Czechoslovak Socialist Republic (ČSSR) and was dominated by the now historical Soviet Union, and the Western bloc comprising democracies such as Austria. The Iron Curtain, a heavily guarded and deadly border zone, separated the two blocs and constrained, in prison style, the populations of the Eastern bloc. The present neuropathological article relates the sad fate of František Faktor, a 33 years-old Czech who was shot by ČSSR border guards when attempting to flee to Austria at the border between and .
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