The Direct Approach: Enones possessing appendant allylic carbonates react directly with diorganozinc reagents in the presence of zinc diiodide [ZnI(2)] to provide 5- and 6-membered ring products of tandem or domino conjugate addition-cycloallylation in good to excellent yield. In a related copper-free transformation, allylic carbonates are found to engage in direct allylic substitution with diorganozinc reagents.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2865154 | PMC |
| http://dx.doi.org/10.1002/adsc.200800242 | DOI Listing |
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