Two dose-finding studies and one open label safety study with a paediatric FSME-IMMUN formulation were conducted in children and adolescents aged 1-15 years (N=3697). The 1.2 microg antigen dose was identified as the optimal dose, inducing high seroconversion rates following the primary vaccination series. Adolescents (aged 12-15 years) vaccinated with the optimal paediatric dose (1.2 microg) attained similarly high seroprotective rates to adults (aged 16-35 years) vaccinated with the 2.4 microg formulation of FSME-IMMUN. We concluded that the FSME-IMMUN paediatric vaccine formulation is safe and highly immunogenic, not only for children <12 years, but also for adolescents <16 years.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.vaccine.2010.04.075 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Factors Associated with Psychological Well-Being Among Children Under 18 Years Old with Cancer: A Scoping Review.
Psychol Res Behav Manag
January 2025
Department of Pediatric Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, West Java, Indonesia.
Background: Cancer diagnosis and treatment can have severe psychological impacts on children that can affect various aspects of their emotional, social and cognitive functioning. Many children with cancer experience long-term psychological distresses. The psychological well-being (PWB) is a critical aspect of their overall health.
View Article and Find Full Text PDFPerceptions of Peer and Parental Support: Feasibility of a Physical Activity Intervention for Adolescent Girls.
Int J Exerc Sci
December 2024
College of Health Sciences, Department of Athletic Training and Clinical Nutrition, University of Kentucky, Lexington, KY, USA.
Physical activity (PA) has a wide range of health benefits. Children with high levels of social support are more likely to achieve adequate levels of PA. The purposes of this pilot study were to examine the impact of an after-school intervention on perceived peer and parental support among adolescent girls and to identify correlates of support to explore in future studies to increase PA.
View Article and Find Full Text PDFPredicting Reliable Improvements in Primary Care Youth Mental Health.
Early Interv Psychiatry
January 2025
Jigsaw: The National Centre for Youth Mental Health, Dublin, Ireland.
Background: Amid a youth mental health crisis, community-based early intervention services have shown promising outcomes. Understanding the specific factors that predict clinical outcomes is crucial for enhancing intervention efficacy, yet these factors remain insufficiently understood.
Aim: This study examined the individual and service-related factors associated with reliable improvement for young people (n = 4565) aged 12-25 years attending a brief primary care youth talk therapy mental health service across 14 sites.
Etiology and Clinical Prediction of Community-Acquired Lower Respiratory Tract Infection in Children.
J Korean Med Sci
January 2025
Department of Pediatrics, Seoul National University Bundang Hospital and Seoul National University College of Medicine, Seongnam, Korea.
Background: Community acquired lower respiratory tract infection (LRTI) is a leading cause for hospitalization in children and important cause for antibiotic prescription. We aimed to describe the aetiology of LRTI in children and analyse factors associated with bacterial or viral infection.
Methods: Patients aged < 19 years with a diagnosis of LRTI were identified from the Observational Medical Outcomes Partnership Common Data Model Database of Seoul National University Bundang Hospital from January 2005-July 2019, and their clinical characteristics were obtained from the electronic medical records and retrospectively reviewed.
[Research on the life stress and hypertension among young couples of childbearing age].
Zhonghua Xin Xue Guan Bing Za Zhi
January 2025
National Research Institute for Health and Family Planning, Beijing100081, China.
To investigate the current status of life stress and hypertension among couples of childbearing age across diverse economic regions in China, and to explore relevant influencing factors. This study was a cross-sectional study, with subjects from the "Research on the standardized system of comprehensive prevention and control of birth defects based on preconception-prenatal-postnatal whole chain". From February to May 2021, urban and rural couples of childbearing age (18-49 years old) from Beijing, Henan, and Gansu provinces were enrolled, representing the eastern, central, and western regions of China, respectively.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!