Methicillin-resistant Staphylococcus aureus (MRSA) is a serious threat to patients in health care facilities and the community. A MRSA infection can be much more severe than other bacterial infections and can be life-threatening. Resistance to common antibiotics makes treating MRSA costly and difficult. Prolonged hospitalization requiring specialized IV antibiotics also has cost implications. Treatment of MRSA can include use of antibiotics; topical therapies such as honey, topical silver, and gentian violet; and bacteriophages. Research is being conducted on new antibiotics and a MRSA vaccine.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.aorn.2009.11.065 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
One-step spray pyrolysis synthesis of ZnO/Ag hollow spheres for enhanced visible-light-driven antibacterial applications and wound healing.
Dalton Trans
January 2025
Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, 030032, China.
ZnO/Ag hollow particles were synthesized a one-step spray pyrolysis method for enhanced antibacterial activity and wound healing applications. The hollow structure and uniform distribution of Ag nanoparticles within the ZnO matrix were confirmed by X-ray diffraction (XRD), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS). UV-Vis spectroscopy and Tauc plot analysis revealed a reduction in the bandgap, attributed to the surface plasmon resonance (SPR) of Ag, improving light absorption in the visible range.
View Article and Find Full Text PDFThe combined use of lytic bacteriophages with antibiotics is currently being explored as a strategy to enhance the effectiveness of infectious disease therapies, including those caused by . In this study, we investigated the synergistic potential of bacteriophage vB_SauM-515A1 ( family) and the first-line antibiotic linezolid against the methicillin-resistant strain SA0413Rev. A checkerboard assay revealed a significant synergistic effect against planktonic cells (FIC = 0.
View Article and Find Full Text PDFImpact of stewardship pharmacist driven MRSA nasal surveillance and de-escalation of anti-MRSA therapy (STEW PHARM MRSA NASAL SURVEILLANCE).
Antimicrob Steward Healthc Epidemiol
December 2024
Department of Pharmacy, Saint Francis Hospital and Medical Center, Hartford, CT, USA.
Objective: To determine if implementing stewardship pharmacist-driven methicillin-resistant (MRSA) nasal surveillance increases use of the test and reduces the inappropriate use of vancomycin for MRSA coverage in patients with pneumonia.
Design: Retrospective pre-/post-intervention study.
Setting: Large teaching acute care hospital.
In Situ Formation of Hydrogels Loaded with ZnO Nanoparticles Promotes Healing of Diabetic Wounds in Rats.
ACS Omega
December 2024
The Third Affiliated Hospital of Anhui Medical University, The First People's Hospital of Hefei, Anhui, Hefei 230000, China.
The challenge of healing diabetic skin wounds presents a significant hurdle in clinical practice and scientific research. In response to this pressing concern, we have developed a temperature-sensitive, in situ-forming hydrogel comprising poly(-isopropylacrylamide---butyl acrylate) -poly(ethylene glycol) -poly(-isopropylacrylamide--butyl acrylate) copolymer, denoted as PEP, in combination with zinc oxide nanoparticles, forming what we refer to as PEP-ZnO hydrogel. The antimicrobial properties of the PEP-ZnO hydrogel against methicillin-resistant were rigorously assessed by using the bacteriostatic banding method.
View Article and Find Full Text PDFKnowledge, Attitude, and Practice Towards Antibiotics Use Among Medical Sector Final-Year Students in Egypt.
Med Sci Educ
December 2024
Faculty of Pharmacy, Clinical Pharmacy Department, Cairo University, Kasr El Einy Street, Cairo, 11562 Egypt.
Introduction: Medical sector students must be well-educated and competent to spread public awareness of antibiotics among the public to combat antibiotic resistance. This study aimed to assess the knowledge, attitude, and practice (KAP) of students regarding antibiotic use and resistance in Egypt.
Methodology: A cross-sectional questionnaire was specially designed and self-administered by final-year students (medicine (MS), pharmacy (PS), dentistry (DS), and nursing (NS)) during the last semester at nine universities.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!