Protracted diarrhea is used to describe infants with loose and frequent stools of sufficient severity to require nutritional support, most commonly parenteral nutrition. Despite similar clinical presentations, the causes of protracted diarrhea in infants are varied and diverse in management and prognosis. The following cases represent the two more common causes of protracted diarrhea in young infants in the developed world - allergic and autoimmune enteropathy. Both patients demonstrate diagnostic challenges related to clinical and/or laboratory features. These cases illustrate the important role histological assessment plays in determining the correct diagnosis, treatment course and prognosis in infants with protracted diarrhea.

Download full-text PDF

Source
http://dx.doi.org/10.3109/15513811003777300DOI Listing

Publication Analysis

Top Keywords

protracted diarrhea
20
protracted
5
diarrhea
5
role histopathology
4
histopathology diagnosing
4
diagnosing protracted
4
diarrhea infancy
4
infancy protracted
4
diarrhea describe
4
infants
4

Similar Publications

Congenital diarrhea and enteropathies (CoDEs) condition is a rare cause of chronic diarrhea in infants that can be challenging to diagnose. This article discusses key signs to recognize in considering a CoDEs diagnosis and provides an overview of the diagnostic process. We report a late preterm twin infant with intractable watery diarrhea starting shortly after birth.

View Article and Find Full Text PDF

Laxative misuse is a well-known occurrence, most often identified in patients struggling with eating disorders. Polyethylene glycol (PEG) 3350 is a readily available, well-tolerated osmotic laxative. High doses of PEG 3350 may cause gastrointestinal upset, diarrhea, dehydration, and electrolyte imbalance, although systemic toxicity is infrequently reported.

View Article and Find Full Text PDF

Cholera continues to cause many outbreaks in low and middle-income countries due to inadequate water, sanitation, and hygiene services. We describe a protracted cholera outbreak in Nairobi City County, Kenya in 2017. We reviewed the cholera outbreak line lists from Nairobi City County in 2017 to determine its extent and factors associated with death.

View Article and Find Full Text PDF

[Analysis of genetic etiology of 234 deaths in the pediatric intensive care unit with suspected genetic diseases].

Zhonghua Er Ke Za Zhi

August 2024

Department of Critical Care Medicine, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai 201102, China.

To explore the genetic etiology of pediatric intensive care unit (PICU) mortality cases and summarize their clinical characteristics. This was a retrospective cohort study. The study population consisted of 234 children who died within 7 d after admitted to the PICU of Children's Hospital of Fudan University from January 2017 to December 2021.

View Article and Find Full Text PDF
Article Synopsis
  • FPIES is a type of food allergy affecting about 0.51-0.9% of children and 0.22% of adults in the U.S., causing severe symptoms like projectile vomiting and diarrhea within hours of eating trigger foods.
  • The most common triggers include cow's milk, oat, rice, avocado, and in some cases, fruits like banana and apple; it can present in various forms, such as acute or chronic, with a generally favorable outcome for infants.
  • Diagnosis is challenging due to a lack of specific biomarkers, and management involves avoiding trigger foods, monitoring tolerance, and treating acute episodes with hydration and antiemetics.
View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!