Objective: In order to analysis the main factors of measles prevalence in 2008, and to provide evidence for establishing scientific strategies on measles elimination.

Methods: 1:1 matched case-control study was conducted in 3 cities, and the conditional logistic regression was used to analyse the risk factor of measles.

Results: 358 matched pairs (716 objects) were investigated. Floating population, hospital exposure were related factors by single factor conditional logistic regression, and multiple factor conditional logistic regression showed the odds ratio of hospital exposure was 2.33 (P < 0.05). Meanwhile, non-immunization was the main possible risk factor in the subjects aged from 8 months to 2 years, which odds ratios for measles was 65.29 (P < 0.05).

Conclusion: Hospital exposure, floating population and existing of non-immunization were the main factor for measles prevalence. It is necesarry to strengthen supervision and education for reducing the exposure opportunities. To perfect the floating population management and ensure the high coverage of 2 dose measles vaccine in children are suggested.

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