In this study, we investigated a novel method for fabrication of carbonate apatite block without ionic movement between precursor and solution by using precursor that includes all constituent ions of carbonate apatite. A powder mixture prepared from dicalcium phosphate anhydrous and calcite at appropriate Ca/P ratios (1.5, 1.67, and 1.8) was used as starting material. For preparation of specimens, the slurry made from the powder mixture and distilled water was packed in a split stainless steel mold and heat - treated, ranging from 60 degrees C to 100 degrees C up to 48 hours at 100% humidity. It appeared that carbonate apatite could be obtained above 70 degrees C and monophasic carbonate apatite could be obtained from the powder mixture at Ca/P ratio of 1.67. Carbonate content of the specimen was about 5-7%. Diametral tensile strength of the carbonate apatite blocks slightly decreased with increasing treatment temperature. The decrease in diametral tensile strength is thought to be related to the crystal size of the carbonate apatite formed.

Download full-text PDF

Source
http://dx.doi.org/10.4012/dmj.2009-095DOI Listing

Publication Analysis

Top Keywords

carbonate apatite
28
powder mixture
12
fabrication carbonate
8
apatite block
8
dicalcium phosphate
8
carbonate
8
apatite powder
8
diametral tensile
8
tensile strength
8
apatite
7

Similar Publications

Mild hypophosphatasia (HPP) can be difficult to distinguish from other bone disorders in the absence of typical symptoms such as the premature loss of primary teeth. Therefore, this study aimed to analyze the crystallinity of hydroxyapatite (HAp) and the three-dimensional structure of collagen in HPP teeth at the molecular level and to search for new biomarkers of HPP. Raman spectroscopy was used to investigate the molecular structure, composition, and mechanical properties of primary teeth from healthy individuals and patients with HPP.

View Article and Find Full Text PDF

Deciphering the mineral code of urinary stones: A first look at zinc isotopes.

Environ Pollut

December 2024

Nu Instruments, Wrexham Industrial Estate, 74 Clywedog Road South, Wrexham, LL13 9XS, United Kingdom.

Zinc (Zn) is an essential element for all living organisms, and Zn isotopes play a key role in studying the formation of disease. Despite extensive studies on Zn isotopes in healthy and diseased human tissues, the role of Zn isotopes in urinary stones remains unexplored. This study investigates Zn isotopes in 37 urinary stones using multi-collector inductively coupled plasma mass spectrometry.

View Article and Find Full Text PDF

Naked siRNAs are sensitive to enzymatic degradation, phagocytic entrapment, quick renal excretion, membrane impermeability, endosomal escape, and off-target effects. Designing a safe and efficient nanocarrier for siRNA delivery to the target site without toxicity remains a significant hurdle in gene therapy. CA is a unique derivative of hydroxyapatite and a highly pH-sensitive nanocarrier with strong particle aggregation and a high polydispersity index.

View Article and Find Full Text PDF

Purpose: To evaluate the effectiveness of COAp granules in the mandibular bone defects by using computed tomography (CT) images.

Methods: This study was retrospective case series of mandibular bone defect reconstruction using COAp granules. Six patients with jawbone cysts treated by simultaneous grafting COAp granules after cyst enucleation were enrolled.

View Article and Find Full Text PDF

Aims: This preclinical study aimed to evaluate the periodontal tissue regenerative capacities of poly (lactic acid/caprolactone) (PLCL) bilayer membrane in one-wall intrabony defects in dogs. No study has assessed the efficacy of PLCL bilayer membrane for periodontal regeneration therapy despite the fact that PLCL bilayer membrane has proved efficient for bone regeneration.

Methods: In five beagle dogs, the bilateral mandibular second and fourth premolars were extracted 8 weeks before the experimental surgery.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!