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Background: Low-middle income countries harbor the highest burden of cardiovascular diseases globally, but there is an under-representation of these countries in cardiovascular clinical trials. This limits the generalizability of the trial results to these countries. There is a lack of data on insights of cardiologists in these countries regarding conducting and participating in clinical trials.

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Introduction: Various studies have demonstrated large variations in the annual occupational exposure of medical personnel working in interventional cardiology departments, ranging from 0.1 mSv to exceeding the annual effective occupational dose limit of 20 mSv.

Purpose: The purpose of this study was to investigate the 17-year dynamics in the personal dosimetry records of the medical staff in one interventional cardiology department in Bulgaria.

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Prenatal detection of cardiac abnormalities has increased significantly over the past few decades, such that fetal cardiology has developed into a sub-specialty of paediatric and congenital cardiology. As this speciality develops further and extends across Europe and more globally, it is important to standardize the requirements for training and subsequent practice, to optimize prenatal diagnosis and perinatal care. In addition to the knowledge and technical skills required to make a correct diagnosis, the counseling of families after diagnosis and the planning of appropriate perinatal management is equally important.

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The aging heart in focus: The advanced understanding of heart failure with preserved ejection fraction.

Ageing Res Rev

November 2024

Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, National Health Commission Key Laboratory of Chronobiology, Development and Related Diseases of Women and Children Key Laboratory of Sichuan Province, Children's Medicine Key Laboratory of Sichuan Province, State Key Laboratory of Biotherapy, West China Second University Hospital, Sichuan University, No.2222 Xinchuan Road, Chengdu 610041, China. Electronic address:

Heart failure with preserved ejection fraction (HFpEF) accounts for 50 % of heart failure (HF) cases, making it the most common type of HF, and its prevalence continues to increase in the aging society. HFpEF is a systemic syndrome resulting from many risk factors, such as aging, metabolic syndrome, and hypertension, and its clinical features are highly heterogeneous in different populations. HFpEF syndrome involves the dysfunction of multiple organs, including the heart, lung, muscle, and vascular system.

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Article Synopsis
  • This study evaluates global differences in the diagnosis and treatment of heart failure with preserved ejection fraction (HFpEF) through an international survey of 1459 physicians, including both cardiologists and non-cardiologists.
  • The survey revealed significant regional variations in HFpEF management, such as differences in natriuretic peptide usage and echocardiographic practices, with cardiologists managing the majority of HFpEF patients.
  • The preferred treatment methods varied by region, with sodium glucose co-transporter-2 inhibitors (SGLT2i) being the most favored first-line treatment, though availability of these drugs differs significantly across locations.
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