Genetic characterization of genogroup I norovirus in outbreaks of gastroenteritis.

J Clin Microbiol

Virus Reference Department, Centre for Infections, Health Protection Agency, Colindale, London, United Kingdom.

Published: July 2010

AI Article Synopsis

  • The P2 domain of norovirus genogroup I (GI) strains shows variations that help identify unrelated outbreaks.
  • Conversely, high conservation in this region enables researchers to trace strains belonging to the same outbreak.
  • This differentiation is crucial for understanding and managing norovirus infections more effectively.

Article Abstract

In this study, we demonstrate that differences within the P2 domain of norovirus genogroup I (GI) strains can be used to segregate outbreaks which are unrelated, whereas complete conservation within this region allows tracking of strains that are part of a single outbreak and likely to have a common source.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2897532PMC
http://dx.doi.org/10.1128/JCM.00798-10DOI Listing

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