Vitamin D receptors have recently been identified in immune cells as well as various parts of the brain. Vitamin D deficiency seems to be involved in the patho-immunological process of multiple sclerosis. Hypovitaminosis D has also been associated with different psychiatric conditions, including depression and schizophrenia. Results from more than 250 publications concluded that patients with both schizophrenia and bipolar condition are more frequently born in winter and spring, the periods which have the largest maternal decline in plasma concentrations of vitamin D.
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