Chronic recurrent abdominal pain is a common complaint evaluated by pediatricians, and a cause of concern for children and parents. Population and school based studies have reported that approximately 8% of children experience chronic abdominal pain. About half of these children will contact a physician about their pain. These children report reduced quality of life and interferences with school and play due to their pain. The large majority of children will not have a readily identified cause for their symptoms, and chronic abdominal pain is frequently classified as a functional gastrointestinal disorder (FGID). The below case study illustrates the presentation, evaluation, and clinical management of a child with chronic abdominal pain.
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Pharmaceuticals (Basel)
January 2025
Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
Canakinumab, a humanized anti-IL-1β monoclonal antibody, is known for its ability to suppress IL-1β-mediated inflammation. However, continuous monitoring of its safety remains essential. Thus, we comprehensively evaluated the safety signals of canakinumab by data mining from FAERS.
View Article and Find Full Text PDFSensors (Basel)
January 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, London SE1 7EH, UK.
Ultrasound imaging is widely valued for its safety, non-invasiveness, and real-time capabilities but is often limited by operator variability, affecting image quality and reproducibility. Robot-assisted ultrasound may provide a solution by delivering more consistent, precise, and faster scans, potentially reducing human error and healthcare costs. Effective force control is crucial in robotic ultrasound scanning to ensure consistent image quality and patient safety.
View Article and Find Full Text PDFJ Clin Med
January 2025
Division of Pediatric Gastroenterology, Hepatology and Nutrition, UH Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, OH 44106, USA.
: To analyze the clinical characteristics, trends in hospitalization, and healthcare resource utilization of pediatric patients with fecal impaction. : We utilized the Healthcare Cost and Utilization Project (HCUP) databases, including the National Inpatient Sample (NIS) and the Kids Inpatient Database (KID) datasets from 2011 to 2019, to include all hospitalizations of patients up to 18 years of age with a primary diagnosis of (1) fecal impaction or (2) a primary diagnosis of abdominal pain or constipation with a secondary diagnosis of fecal impaction. The study analyzed various comorbid factors and clinical characteristics of these patients.
View Article and Find Full Text PDFJ Clin Med
January 2025
Surgical Science Department, Plastic and Reconstructive Surgery Unit, "Pugliese-Ciaccio" Hospital, 88100 Catanzaro, Italy.
Incisional ventral hernia repair remains a challenging surgery for abdominal wall surgeons. We report the results at 48 months post-surgery regarding open ventral hernia repair (OVHR), analyzing the recurrence rate and incidence of chronic pain. This was a retrospective, observational study of 111 consecutive patients who underwent OVHR.
View Article and Find Full Text PDFJ Clin Med
January 2025
Department of Gynecology and Obstetrics, University Hospital RWTH Aachen, 52074 Aachen, Germany.
: Endometriosis is a chronic gynecological disorder characterized by ectopic endometrial-like tissue. The symptoms of this disease negatively affect the patient's quality of life, both physically and mentally. This study aims to identify key factors impacting health-related quality of life in endometriosis patients.
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