AI Article Synopsis
- The study evaluates the long-term eye health outcomes of six children diagnosed with tumor-related Parinaud syndrome between 2000 and 2007, all experiencing symptoms of increased intracranial pressure.
- The children received treatments including surgical shunting, complete or partial tumor resection, and additional therapies like chemotherapy and radiation, with most showing stable or improved vision after treatment.
- Follow-up after an average of 4.2 years revealed some persistent eye issues in most patients, highlighting that children may have lasting, though subtle, eye problems even after successful treatment of Parinaud syndrome.
Article Abstract
Background And Objective: To assess the long-term ophthalmological outcome of Parinaud syndrome.
Patients And Methods: The files of 6 children with tumor-related Parinaud syndrome diagnosed and observed from 2000 to 2007 were reviewed. All had papilledema indicating increased intracranial pressure.
Results: Mean presentation-to-diagnosis delay was 3.6 weeks. Treatment consisted of surgical shunting and complete or partial resection with adjuvant chemotherapy (n = 4) and radiation (n = 3). Visual acuity remained stable or improved in 8 of 9 eyes with 20/30 visual acuity at diagnosis; improved bilaterally in 1 patient from 20/100 to 20/25; and deteriorated bilaterally in 1 patient from 20/30 and 20/200 to counting fingers and hand motions, respectively. The most improvement was achieved within 4 months. Findings at follow-up (mean: 4.2 years) included up gaze limitation (minimal in 2 patients), abnormal convergence, convergence retraction nystagmus, and light-near dissociation. One child had bilateral optic atrophy.
Conclusion: Children with tumor-related Parinaud syndrome tend to have subtle but measurable residual ophthalmological findings years after diagnosis and treatment.
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| http://dx.doi.org/10.3928/15428877-20100426-02 | DOI Listing |
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