Ceramide-mediated transport of chloride and bicarbonate across phospholipid membranes.

Chem Commun (Camb)

Department of Chemistry and Biochemistry, University of Maryland, College Park, MD 20740, USA.

Published: June 2010

The sphingolipid, ceramide 1, facilitates transport of Cl(-) and HCO(3)(-) anions across lipid bilayers under conditions where large transmembrane pores are not formed. Ceramide's 1,3-diol unit is essential for both binding and transporting these anions.

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Source
http://dx.doi.org/10.1039/c0cc00493fDOI Listing

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