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An unusual case of eosinophilia, myalgia and skin contractures: Shulman's disease revisited.
Med J Armed Forces India
September 2022
Senior Resident (Medicine), Command Hospital (Air Force), Bengaluru, India.
Shulman's disease (eosinophilic fasciitis) is a very rare autoimmune disorder with an unknown etiopathogenesis. During the initial period of disease, it usually causes limb and trunk edema followed by collagenous thickening of the subcutaneous fascia. Eosinophilia is a predominant laboratory finding during the initial phase of the disease and less prominent in the later phases.
View Article and Find Full Text PDFNot just eosinophilic fasciitis.
J Med Life
April 2021
Department of Gastroenterology, Bucharest Emergency University Hospital.
Article Synopsis
- - A 65-year-old male with a history of eosinophilic fasciitis experienced progressive muscle weakness despite ongoing treatment, leading to further evaluation at the Mayo Clinic.
- - Imaging revealed significant changes in the thigh muscles, prompting the need for biopsies to investigate the cause of the muscle weakness.
- - The case highlights the importance of considering additional autoimmune conditions, such as myopathy, in patients with eosinophilic fasciitis who present with unusual muscle weakness symptoms.
[Hypereosinophilic syndrome and other rheumatic diseases with hypereosinophilia].
Z Rheumatol
May 2019
Klinik für Innere Medizin I, Sektion Rheumatologie, Exzellenzzentrum Entzündungsmedizin, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold-Heller-Str. 3, 24105, Kiel, Deutschland.
Among the eosinophilic diseases treated by rheumatologists other than eosinophilic granulomatosis with polyangiitis, there are further organ-related and systemic diseases with hypereosinophilia. Only the exact differential diagnostic demarcation of the diseases enables a pathogenetic oriented treatment. This article focuses on the hypereosinophilic syndromes.
View Article and Find Full Text PDFPossible Parkinson's Disease Induced by Chronic Manganese Supplement Ingestion.
Consult Pharm
December 2016
Objective: The objective is to report a case of possible neurotoxicity resulting from an incorrect dietary supplement for osteoporosis taken at a toxic dose.
Summary: The case study examined here is a 37-year-old African-American female who consumed excessive manganese over a period of years, resulting in Parkinson's disease (PD). This patient was referred to the pharmacist pharmacotherapy service by a neurology physician.
[Eosinophilic fasciitis (Shulman's disease): Diagnostic and therapeutic review].
Rev Med Interne
November 2015
Université Paris-Cité Sorbonne Paris-Diderot, 75013 Paris, France; Service de médecine interne, hôpital Lariboisière, AP-HP, 2, rue Ambroise-Paré, 75475 Paris cedex 10, France. Electronic address:
Eosinophilic fasciitis (EF) is a rare connective tissue disease characterized by symmetrical and painful swelling with a progressive induration and thickening of the skin and soft tissues. The diagnosis of EF is often based on the association of characteristic skin or subcutaneous abnormalities and a thickened fascia with an inflammatory infiltration, mostly composed of lymphocytes and eosinophils. A peripheral eosinophilia is frequently present (60-90%) but is not mandatory for the EF diagnosis.
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