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Convergence of Hypervirulence and Multidrug-Resistance in Complex Isolates from Patients with COVID-19.
Infect Drug Resist
December 2024
Department of Medical Laboratory, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong, People's Republic of China.
Article Synopsis
- This study examines the prevalence of co-infections with Burkholderia cepacia complex (Bcc) in patients with respiratory infections like COVID-19 and H7N9, highlighting a lack of previous research on this topic.
- A total of 49 Bcc isolates were analyzed from patients, revealing that those infected with COVID-19 had a higher rate of multidrug resistance and a shorter median lethal time compared to those with H7N9.
- The findings suggest that COVID-19-Bcc may have evolved from H7N9-Bcc, demonstrating increased virulence and antibiotic resistance in the context of respiratory infections.
Primary cutaneous melioidosis - A rare case needing intensive care unit admission.
South Afr J Crit Care
July 2024
Department of Critical Care Medicine, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
Background: Melioidosis cases are increasing in Southeast Asia, posing a significant challenge owing to the rising number of diabetic and immune compromised patients. Pneumonia is the most common presentation of melioidosis, while cutaneous melioidosis is rare.
Objectives: We report a case of primary cutaneous melioidosis (PCM) that eventually required intensive care unit (ICU) management.
Severe bongkrekic acid poisoning caused by eating spoiled Auricularia auricula: a case report.
BMC Complement Med Ther
December 2024
Department of Occupational and Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, 250012, China.
Background: Bongkrekic acid is a rare mitochondrial toxin produced by the Burkholderia cocovenenans subsp. Bongkrekic acid poisoning has a case fatality rate of more than 50%, and progresses rapidly to multiple organ failure. However, limited clinical information is available regarding this phenomenon.
View Article and Find Full Text PDFProsthetic valve infective endocarditis due to Burkholderia pseudomallei: A case report and review of the literature.
Acta Trop
January 2025
Department of Medicine, Cairns Hospital, Cairns, Queensland Australia; Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia. Electronic address:
Endocarditis is a very rare complication of Burkholderia pseudomallei infection and prosthetic valve endocarditis rarer still. We present, to our knowledge, the first confirmed Australian case of prosthetic valve endocarditis in a patient with melioidosis. Blood cultures were persistently positive for B.
View Article and Find Full Text PDFMycotic aneurysms due to Burkholderia pseudomallei in Far North Queensland, tropical Australia: A case series and review of the literature.
Acta Trop
December 2024
Department of Medicine, Cairns Hospital, Cairns, Queensland, Australia; The Kirby Institute, University of New South Wales, Sydney, NSW, Australia. Electronic address:
Since 2019, Burkholderia pseudomallei has been the most common cause of mycotic aneurysm at Cairns Hospital in tropical Australia. Among 233 culture-confirmed cases of melioidosis since this time, 8 (3.4 %) were diagnosed with a mycotic aneurysm.
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