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Cost-Effective Drug Testing: Analytical Methodology, Best Practices, and Clinical Utility.
J Appl Lab Med
January 2025
Department of Pathology and Laboratory Medicine, UC Davis Health, Sacramento, CA, United States.
Background: Drug overdose-related deaths continue to increase globally. Testing demands have likewise increased, prompting healthcare facilities to adopt a range of methods, from simple point-of-care immunoassays to comprehensive chromatographic and mass spectrometry-based techniques. Each of these testing methods has trade-offs related to cost, performance, speed, and convenience, requiring healthcare facilities to carefully determine the best options to meet their clinical needs.
View Article and Find Full Text PDFIncorporating Economic Evidence in Clinical Guidelines: A Framework From the Clinical Guidelines Committee of the American College of Physicians.
Ann Intern Med
December 2024
David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California (C.J.C.).
In recognition of accelerating health care spending and alignment with the American College of Physicians (ACP) principles of promoting high-value care, the ACP Clinical Guidelines Committee (CGC) developed a framework to standardize its approach to identifying, appraising, and considering economic evidence in the development of ACP clinical guidelines. This article presents the CGC's process for incorporating economic evidence, which encompasses cost-effectiveness analyses, economic outcomes in randomized controlled trials, and resource utilization (intervention cost) data. Economic evidence is one component of ACP recommendations.
View Article and Find Full Text PDFNeutrophil-to-lymphocyte, platelet-to-lymphocyte ratios and systemic immune-inflammation index in patients with post-traumatic stress disorder.
BMC Psychiatry
December 2024
Etlik City Hospital, Psychiatry Clinic, Ankara, Turkey.
Background: Low-grade systemic inflammation has been reported in many psychiatric diseases and is described as a non-severe state of the inflammatory response. Post-traumatic stress disorder (PTSD) is a chronic psychiatric disorder characterized by symptoms of avoidance, re-experiencing and hyperarousal that develop secondary to a serious traumatic event. The trauma itself creates psychological and biological changes in the individual, apart from PTSD.
View Article and Find Full Text PDFChildren's cost-benefit analysis about agents who act for the greater good.
Cognition
December 2024
Department of Psychology & Neuroscience, Duke University 417 Chapel Drive, Box 90086, Durham, NC 27708, USA. Electronic address:
Acting for the greater good often involves paying a personal cost to benefit the collective. In two studies, we investigate how children (N = 184, M = 8.02 years, SD = 1.
View Article and Find Full Text PDFClinical comparative study of robot-assisted and traditional laparoscopic surgery in patients with cervical cancer: a retrospective cohort study.
BMC Surg
December 2024
Department of Phase I Clinical Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Background: A new era in minimally invasive surgery has been ushered in by Leonardo's robot surgical system, but the safety and effectiveness in cervical cancer is lake of evidence. This study aimed to compare the safety, effectiveness, and cost-effectiveness of robot-assisted laparoscopic radical hysterectomy (RRH) and conventional laparoscopic radical hysterectomy (LRH) in patients with cervical cancer.
Methods: Patients with cervical cancer who had radical surgery at the first affiliated Hospital of Chongqing Medical University between January 2017 and June 2022 were enrolled.
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