To examine whether any correlation exists between the levels of circulating immune complexes (CICs) and the activity of tuberculosis, CICs were measured in the sera of 75 patients with active tuberculosis and in 25 control subjects using polyethylene glycol method. The effect of drug treatment on the levels of CICs was also estimated in 25 patients. It was found that levels of CICs were elevated in most of the untreated patients (96%) of tuberculosis and the CICs levels fell to control values in 64% of patients at the end of treatment.
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