Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Using the Box-Behnken experimental design to optimise operating parameters in pulsed spray fluidised bed granulation.
Int J Pharm
May 2013
School of Pharmacy, De Montfort University, Leicester LE1 9BH, UK.
In this work, the influence factors of pulsed frequency, binder spray rate and atomisation pressure of a top-spray fluidised bed granulation process were studied using the Box-Behnken experimental design method. Different mathematical models were developed to predict the mean size of granules, yield, relative width of granule distribution, Hausner ratio and final granule moisture content. The study has supported the theory that the granule size can be controlled through the liquid feed pulsing.
View Article and Find Full Text PDFThe top-spray fluidised bed coating process: a new quality model.
Commun Agric Appl Biol Sci
May 2010
Department of Biosystems Engineering, Ghent University, Coupure Links 653, 9000 Gent, Belgium.
Effect of maximum packing limit on granular flow pattern in the top-spray fluidised bed coater.
Commun Agric Appl Biol Sci
January 2009
Biosystems Engineering, Ghent University.
A new process control strategy for aqueous film coating of pellets in fluidised bed.
Eur J Pharm Sci
November 2003
Process Technology Development, Ferring A/S, Indertoften 10, DK-2720 Vanløse, Denmark.
The parameters with effect on maximum spray rate and maximum relative outlet air humidity when coating pellets in a fluidised bed were investigated. The tested variables include type of water based modified release film coating (Eudragit NE 30D, Eudragit RS 30D, Aquacoat ECD) coating principle (top spray, bottom spray), inlet air humidity and type of pellets (sugar spheres, microcrystalline cellulose pellets). The maximum spray rate was not influenced by the coating principles.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!