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Using group model building to frame the commercial determinants of dietary behaviour in adolescence - findings from online system mapping workshops with adolescents, policymakers and public health practitioners in the Southwest of England.
BMC Public Health
January 2025
National Institute for Health Research (NIHR) School for Public Health Research (SPHR), Newcastle, UK.
Background: In England, 23% of children aged 11 start their teenage years living with obesity. An adolescent living with obesity is five times more likely to live with obesity in adult life. There is limited research and policy incorporating adolescents' views on how they experience the commercial determinants of dietary behaviour and obesity, which misses an opportunity to improve services and policies that aim to influence the prevalence of childhood obesity.
View Article and Find Full Text PDFSuperconductive Coupling Effects in Selectively Grown Topological Insulator-Based Three-Terminal Junctions.
ACS Nano
January 2025
Peter Grünberg Institut (PGI-9), Forschungszentrum Jülich, 52425 Jülich, Germany.
The combination of an ordinary s-type superconductor with three-dimensional topological insulators creates a promising platform for fault-tolerant topological quantum computing circuits based on Majorana braiding. The backbone of the braiding mechanism are three-terminal Josephson junctions. It is crucial to understand the transport in these devices for further use in quantum computing applications.
View Article and Find Full Text PDFA combinatory approach of non-chain ring and henon map for image encryption application.
Sci Rep
January 2025
Department of Mathematics, College of Science, King Khalid, University, Abha, 61413, Saudi Arabia.
Algebraic structures play a vital role in securing important data. These structures are utilized to construct the non-linear components of block ciphers. Since constructing non-linear components through algebraic structures is crucial for the confusion aspects of encryption schemes, relying solely on these structures can result in limited key spaces.
View Article and Find Full Text PDFLongitudinal serum proteome mapping reveals biomarkers for healthy ageing and related cardiometabolic diseases.
Nat Metab
January 2025
Westlake Center for Intelligent Proteomics, Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.
The blood proteome contains biomarkers of ageing and age-associated diseases, but such markers are rarely validated longitudinally. Here we map the longitudinal proteome in 7,565 serum samples from a cohort of 3,796 middle-aged and elderly adults across three time points over a 9-year follow-up period. We pinpoint 86 ageing-related proteins that exhibit signatures associated with 32 clinical traits and the incidence of 14 major ageing-related chronic diseases.
View Article and Find Full Text PDFInvolvement of p38 MAPK and MAPKAPK2 in promoting cell death and the inflammatory response to ischemic stress associated with necrotic glioblastoma.
Cell Death Dis
January 2025
Division of Hematology and Oncology, Department of Pediatrics, Penn State College of Medicine, Hershey, PA, USA.
The association of necrosis in tumors with poor prognosis implies a potential tumor-promoting role. However, the mechanisms underlying cell death in this context and how damaged tissue contributes to tumor progression remain unclear. Here, we identified p38 mitogen-activated protein kinases (p38 MAPK, a.
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