In patients with functional disorders of the stomach and chronic gastroduodenitis, the content of cellular bioregulaters (prostaglandins) in the blood and gastric mucosa was abnormal. The revealed alterations may give rise to a reduction of mucosal resistance because of cytoprotection weakening and derangement of the control over gastric secretion. The data obtained make great contributions to our concepts of the pathogenesis of gastroduodenal pathology and children and provide evidence for new approaches to its prevention and treatment.
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