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Mechanisms of Low Temperature Thickening of Different Materials for Deepwater Water-Based Drilling Fluids.
Gels
December 2024
School of Petroleum Engineering, China University of Petroleum (East China), Qingdao 266580, China.
During deepwater drilling, the low mudline temperatures and narrow safe density window pose serious challenges to the safe and efficient performance of deepwater water-based drilling fluids. Low temperatures can lead to physical and chemical changes in the components of water-based drilling fluids and the behavior of low temperature gelation. As a coarse dispersion system, water-based drilling fluid has a complex composition of dispersed phase and dispersing medium.
View Article and Find Full Text PDFAripiprazole-loaded niosome/chitosan-gold nanoparticles for breast cancer chemo-photo therapy.
BMC Biotechnol
December 2024
Department of Microbiology, Faculty of Veterinary and Agriculture, Islamic Azad University, Shabestar Branch, Shabestar, Iran.
Introduction: Breast cancer, a formidable global health challenge for women, necessitates innovative therapeutic strategies with enhanced efficacy and minimal side effects. Aripiprazole (ARI), a widely used schizophrenia medication, exhibits promising potential in the treatment of breast cancer. As cancer therapy evolves towards a combination approach, multimodal nano-based delivery systems, such as ARI-loaded niosomes (NIOs) combined with Chitosan-Au nanoparticles for chemo-photothermal therapy, show promise over traditional chemotherapy alone by enhancing targeted efficacy and minimizing side effects.
View Article and Find Full Text PDFDimensionality reduction of high-solid anaerobic digestion flow pattern: Flow velocity distribution model and control strategy.
Bioresour Technol
December 2024
Laboratory of Reactions and Process Engineering, Université de Lorraine, CNRS, 1, rue Grandville, BP 20451, Nancy Cedex 54001, France.
High-solid anaerobic digestion (HSAD) can be used to treat organic waste. However, the operating stability is limited by the hydraulic conditions; therefore, regulation is essential. The flow field contains a large amount of information that cannot be directly regulated.
View Article and Find Full Text PDFDesign, synthesis, and characterization of an Ag-Bi-S-based multifunctional nanotheranostic platform.
J Mater Chem B
December 2024
College of Biomedical Engineering, Hubei Key Laboratory of Medical Information Analysis and Tumor Diagnosis & Treatment, and Key Laboratory of Cognitive Science of State Ethnic Affairs Commission, South-Central Minzu University, Wuhan 430074, China.
This paper reports an Ag-Bi-S-based nanotheranostic platform with an ingeniously designed heterostructure, an appropriate size, and good imaging and therapy performances. By comparing the fluorescence property and Bi element content, the optimal heterostructure was demonstrated to be AgS/BiS core/shell. The hydrophilic AgS/BiS-PEG nanocrystals with hydrodynamic diameter of 37.
View Article and Find Full Text PDFSpray-dried cyclophosphamide-loaded polyhydroxyalkanoate microparticles: design and characterization.
ADMET DMPK
October 2024
Siberian Federal University, 79 Svobodny pr., Krasnoyarsk 660041, Russia.
Background And Purpose: Cyclophosphamide (CP) is a widely used antitumor and immunosuppressive drug, but it is highly cytotoxic and has carcinogenic and teratogenic potential. To reduce adverse effects of CP therapy and the frequency of its administration, the microencapsulation of CP into biodegradable polymeric matrices can be performed. However, according to the literature, only a few polymers were found suitable to encapsulate CP and achieve its' sustained release.
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