The left ventricular contractility was evaluated in patients with hyperlipidemia or uncomplicated Functional Class I-III angina by using echocardiography at rest and during bicycle ergometric tests. A total of 47 males under 60 years were examined, who were divided into 4 groups: 1) 10 healthy subjects; 2) 14 hyperlipidemic subjects without signs of coronary heart disease; 3) 10 patients with Functional Class I-III angina who showed no ischemic response to bicycle ergometry; and 4) 13 patients with angina pectoris who showed an ischemic response to exercise. The patients had no history of myocardial infarction. The patients from Groups 2-4 displayed a lower overall left ventricular contractility as manifested by no decrease in left ventricular end systolic volume after exercise and other parameters. They also exhibited a segment asynergy in myocardial performance.
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