Objective: Radiologists want to improve quality and safety to benefit their pediatric patients and to comply with new requirements of the American Board of Radiology for maintenance of certification. The purpose for this article is to describe the development, construction, and content of a free, Web-based practice quality improvement (PQI) module in CT safety for children.
Conclusion: We describe an online tutorial accessible on the Image Gently Website that enables radiologists nationwide to perform PQI in CT safety for pediatric patients.
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http://dx.doi.org/10.2214/AJR.09.3764 | DOI Listing |
Cancer immunotherapy using engineered cytotoxic effector cells has demonstrated significant potential. The limited spatial complexity of existing models, however, poses a challenge to mechanistic studies attempting to approve existing approaches of effector cell-mediated cytotoxicity within a three-dimensional, solid tumor-like environment. To gain additional experimental control, we developed an approach for constructing three-dimensional (3D) culture models using smart polymers that form temperature responsive hydrogels.
View Article and Find Full Text PDFFront Plant Sci
December 2024
Department of Plant Biology, Rutgers University, New Brunswick, NJ, United States.
Understanding the early interactions between plants and endophytes will contribute to a more systematic approach to enhancing endophyte-mediated effects on plant growth and environmental stress resistance. This study examined very early growth and ascorbate metabolism after seed treatment of with three different endophytes. The three endophytes used were pb1(Bapb1), (Ml) and SLB4 (SLB4).
View Article and Find Full Text PDFSci Rep
November 2024
Department of Chemistry, School of Chemical & Biotechnology, Shanmugha Arts, Science, Technology & Research Academy (SASTRA) Deemed University, Thanjavur, 613 401, Tamil Nadu, India.
Therapeutic deep eutectic solvents (THEDES) are a type of deep eutectics that can be used as active pharmaceutical ingredients (APIs) by enhancing the drug bioavailability, by increasing the solubility of APIs in aqueous solutions or by increasing their permeability through biological barriers. In this study, we demonstrate the utility of designer THEDES, based on Quillaja Saponin (SAP), a triterpene natural product to unravel the antimicrobial potential of such THEDES. THEDES were prepared by gently mixing and heating five different α- hydroxy acids- malic, citric, tartaric, glycolic, lactic acids and SAP with water as a third component in the THEDES.
View Article and Find Full Text PDFOpen Res Eur
October 2024
National Agency of Hydrocarbon, Bogota, Cundinamarca, 111321, Colombia.
Background: The present contribution reexamines the geometry of a segment of a presumably long-lived fault in Svalbard, the Balliolbreen Fault segment of the Billefjorden Fault Zone, along which presumably two basement terranes of Svalbard accreted in the early-mid Paleozoic after thousands of kilometers strike-slip displacement.
Methods: We performed structural fieldwork to Billefjorden in central Spitsbergen and interpreted satellite images.
Results: Field observations demonstrate that the Balliolbreen Fault formed as a top-west thrust fault in the early Cenozoic and that weak sedimentary units such as shales of the Lower Devonian Wood Bay Formation and coals of the uppermost Devonian-Mississippian Billefjorden Group partitioned deformation, resulting in significant contrast in deformation intensity between stratigraphic units.
Biol Methods Protoc
October 2024
Department of Functional Organization of Biomembranes, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 14220 Prague, Czech Republic.
Fluorescence microscopy images of biological samples contain valuable information but require rigorous analysis for accurate and reliable determination of changes in protein localization, fluorescence intensity, and morphology of the studied objects. Traditionally, cells for microscopy are immobilized using chemicals, which can introduce stress. Analysis often focuses only on colocalization and involves manual segmentation and measurement, which are time-consuming and can introduce bias.
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