Objective: To determine the effectiveness of sit-to-stand training in individuals with stroke.
Design: Randomized controlled trial.
Setting: Rehabilitation medical centre.
Participants: Thirty-two subjects with stroke were randomly assigned to the control and experimental groups (n = 16 for each group).
Interventions: Subjects in both groups received 30 minutes of general physical therapy three times a week for four weeks. Subjects in the experimental group received additional sit-to-stand training for 15 minutes each time. The total amount of therapy received was 45 minutes in the experimental group and 30 minutes in the control group each time.
Main Outcome Measures: The weight-bearing distribution during quiet standing, the directional control and maximal excursion during limits of stability test, the scores of Berg Balance Scale and the extensor muscle strength of lower extremity were assessed before and after completing the 12 treatment sessions.
Results: Our data showed significant improvements in directional control anteriorly in the experimental group (from 47.4 (36.6)% to 62.6 (26.1)%) compared with the control group (from 68.7 (16.7)% to 62.8 (29.7)%) (P = 0.028). A significant improvement in affected hip extensor strength was noted in the experimental group (from 19.3 (9.8)% to 22.6 (8.4)%) compared with the control group (from 24.4 (9.0)% to 22.8 (7.2)%) (P = 0.006). Significant improvements were noted only in the experimental group after treatment, including bilateral extensors, except the affected plantar flexors, the weight distribution in standing, the maximal excursion (P(anterior) = 0.049; P(affected) = 0.023) and the directional control (P(affected) = 0.013; P(non-affected) = 0.025).
Conclusions: Additional sit-to-stand training is encouraged due to effects on dynamic balance and extensor muscles strength in subjects with stroke.
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http://dx.doi.org/10.1177/0269215509360751 | DOI Listing |
Neurol Res
January 2025
Department of Physiology, Faculty of Medicine, Izmir Democracy University, Izmır, Turkey.
Objective: Within the scope of this research, the long-term effects of experimental blunt head trauma on immature rats and MK-801 administered acutely after trauma on the brain tissue will be examined. In addition, the impact of trauma and MK-801 on Nestin and CD133, which are essential stem cells, will be evaluated by immunohistochemical and ELISA methods.
Methods: In this study, the contusion trauma model was used.
Exp Dermatol
January 2025
Department of Dermatology, Kansai Medical University, Hirakata, Osaka, Japan.
Chronic inflammation in the tumour microenvironment (TME) via Th2-polarisation promotes melanoma progression and metastasis, making it a target for immunotherapy. Interleukin (IL)-4 is considered essential for Th2-polarisation in the TME; however, its source remains unknown. Basophils have been postulated as one of its sources.
View Article and Find Full Text PDFMagn Reson Chem
January 2025
Laboratório de Química Computacional e Modelagem Molecular (LQC-MM), Departamento de Química Inorgânica, Instituto de Química, Universidade Federal Fluminense (UFF), Niterói, Rio de Janeiro, Brazil.
We present a DFT-PCM NMR study of 3-indoleacetic acid (3-IAA), used as a working example, including explicit solvent molecules, named PCM-nCHCl, PCM-nDMSO (n = 0, 2, 4, 8, 14, 20, and 25), to investigate the dimer formation in solution. Apart from well-known cyclic (I) and open (II) acetic acid (AA) dimers, two new structures were located on DFT-PCM potential energy surface (PES) for 3-IAA named quasicyclic A (III) and quasicyclic B (IV), the last one having N-H…O hydrogen bond (instead of O-H…O). In addition, four other structures having π-π type interactions named V, VI, VII, and VIII were also obtained completing the sample on the PES.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopedics, Qingdao Municipal Hospital, 1 Jiaozhou Road, Shinan District, QingDao, Shandong Province, 266399, China.
Background: Spacer-type tibial osteotomy have been proven a novel and effective osteotomy to treat osteoarthritis, while lack of comparison with other surgical methods in younger patients. This study aims to evaluate the short-term clinical outcomes of spacer-type tibial osteotomy versus open wedge high tibial osteotomy (OWHTO) and unicompartmental knee arthroplasty (UKA) for Kellgren-Lawrence (K-L) grade 3-4 osteoarthritis (OA) in patients younger than 65 years.
Methods: This retrospective study analyzed a total of 224 patients with K-L grade 3-4 knee OA treated from March 2018 to November 2020.
J Toxicol Environ Health A
January 2025
Hunan Province Key Laboratory of Typical Environmental Pollution and Health Hazards, School of Public Health, University of South China, Hengyang, China.
Inflammatory bowel disease (IBD) is a complex gastrointestinal disorder attributed to genetic and environmental factors. Microcystin-leucine-arginine (MC-LR) is an environmental toxin that accumulates in the gut and produces intestinal damage. The aim of this study was to investigate the effects of exposure to MC-LR on development and progression of IBD as well examine the underlying mechanisms of microcystin-initiated tissue damage.
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