Results of experimental and clinical evaluation of the method of nonspecific hemosorption obtained in the Laboratory of Clinical Immunology and Republican Centre for Application of Extracorporeal Therapies, Research Institute of Physical and Clinical Medicine, since 1985 are presented. Analysis of these and literature data on the efficiency of hemosorption in non-toxicological practice allows for the conclusion of socio-medical and economic feasibility of more extensive application of the method.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Preparation of chitin/MXene/poly(L-arginine) composite aerogel spheres for specific adsorption of bilirubin.
Int J Biol Macromol
July 2023
Department of Materials Science and Engineering, College of Chemistry and Materials Science, Jinan University, Guangzhou 510632, China; Engineering Research Center of Artificial Organs and Materials, Ministry of Education, Guangzhou 510632, China. Electronic address:
Currently, hemoperfusion is clinically the most rapid and effective treatment for removing toxins from the blood. The core of hemoperfusion is the sorbent inside the hemoperfusion device. Due to the complex composition of the blood, adsorbents tend to adsorb substances such as proteins in the blood (non-specific adsorption) while adsorbing toxins.
View Article and Find Full Text PDFRationale for sequential extracorporeal therapy (SET) in sepsis.
Crit Care
February 2023
Center for Critical Care Nephrology, CRISMA, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, 3550 Terrace Street, Pittsburgh, PA, 15261, USA.
Sepsis and septic shock remain drivers for morbidity and mortality in critical illness. The clinical picture of patients presenting with these syndromes evolves rapidly and may be characterised by: (a) microbial host invasion, (b) establishment of an infection focus, (c) opsonisation of bacterial products (e.g.
View Article and Find Full Text PDFHemoperfusion in the intensive care unit.
Intensive Care Med
October 2022
International Renal Research Institute of Vicenza, Vicenza, Italy.
Multiple organ failure following a septic event derives from immune dysregulation. Many of the mediators of this process are humoral factors (cytokines), which could theoretically be cleared by direct adsorption through a process called hemoperfusion. Hemoperfusion through devices, which bind specific molecules like endotoxin or theoretically provide non-specific adsorption of pro-inflammatory mediators has been attempted and studied for several decades with variable results.
View Article and Find Full Text PDFHemoperfusion plus continuous veno-venous hemofiltration in the treatment of patients with multiple organ failure after wasp stings.
Int J Artif Organs
March 2020
Department of Nephrology, Xijing Hospital, Fourth Military Medical University, Xi'an, China.
Purpose: This study aimed to evaluate the clinical effects of hemoperfusion plus continuous veno-venous hemofiltration in the treatment of patients with multiple organ failure after wasp stings and investigate its impacts on cytokines.
Methods: A total of 12 patients with multiple organ failure after wasp stings admitted to Xijing Hospital were included in the present study between January 2017 and January 2019. All patients received hemoperfusion plus continuous veno-venous hemofiltration treatment in addition to conventional treatment after admission.
Clinical characteristics and treatment of thallium poisoning in patients with delayed admission in China.
Medicine (Baltimore)
July 2019
Poisoning Treatment Department, Affiliated Hospital Academy of Military Medical Sciences, Beijing.
Thallium is highly toxic and its effects are cumulative. The clinical symptoms of thallium poisoning are non-specific, thereby delaying admission and treatment. This study aimed to summarize the clinical features and treatment experience of patients with delayed admission who experience thallium poisoning.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!