Candida is the most frequent cause of invasive fungal infections in humans that yield high levels of mortality and health-related costs. Several factors lead to the development of candidemia. The Infectious Diseases Society of America (IDSA) updated its guidelines for the management of candidiasis and proper use of antifungal agents in Candida infections. The echinocandins are novel antifungal 1,3-beta-glucan synthase inhibitors and are currently the first choice treatment for most Candida infections, with good responses to support its use.
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Chempluschem
January 2025
NCSR Demokritos: Ethniko Kentro Ereunas Physikon Epistemon Demokritos, Institute of Physical Chemistry, Patriarchou Gregoriou and Neapoleos, Aghia Paraskevi, Attiki, 15310, Athens, GREECE.
The hydrophilic character and the protection against pathogen proliferation are the most pivotal characteristics of leathers intended for medical purposes. To achieve these goals, dispersions of TiO2 particles incorporating three different formulations of biomimetically synthesized silica xerogels were tested. Emphasis has been given to the role of single and dual solvents employed.
View Article and Find Full Text PDFTranspl Infect Dis
January 2025
Infectious Diseases Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Background: Infections are a common complication among lung transplant recipients (LuTR), particularly in the first year post-transplant, with respiratory tract infections (RTI) being predominant. Syndromic molecular panels have been suggested to reduce morbidity and mortality by providing a diagnosis quickly. However, integrating these panels into clinical practice remains debated.
View Article and Find Full Text PDFColorectal Dis
February 2025
Department of Infectious Diseases, Hospital Universitari Parc Taulí, Sabadell, Spain.
Aim: Oral antibiotic prophylaxis (OAP) lowers rates of surgical site infection (SSI) and may aid anastomotic healing in colorectal surgery. The aim of this study was to analyse the understudied impact of OAP on SSI microbiology after colorectal surgery.
Method: A post hoc analysis was performed on a previous prospective, multicentre study of elective colorectal surgery.
Lasers Surg Med
January 2025
Gynecology Department, Life Memorial Hospital, Medlife Hyperclinic, Bucharest, Romania.
Objectives: To assess the effect of non-ablative Er:YAG laser therapy on the symptoms and microbiological conditions of women with recurrent vulvovaginal candidiasis (RVVC).
Materials And Methods: One hundred and sixty-seven women (mean age 34.1 ± 8.
Pathog Dis
January 2025
Department of Biomedical Sciences.
Chlamydia trachomatis and Candida albicans are common inhabitants of the female genital tract. C. albicans can impact viability and pathogenesis of some bacteria.
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