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Coping After Breast Cancer: Protocol for a Randomized Controlled Trial of Stress Management eHealth Interventions.
JMIR Res Protoc
May 2023
Cancer Registry of Norway, Oslo University Hospital, Oslo, Norway.
Background: One-third or more of breast cancer survivors report stress and other psychological and physical complaints that can negatively impact their quality of life. Psychosocial stress management interventions, shown to mitigate the negative impact of these complaints, can now be delivered as accessible and convenient (for the patient and provider) eHealth interventions. In this randomized controlled trial (RCT), Coping After Breast Cancer (CABC), 2 modified versions of the stress management eHealth intervention program StressProffen were created: one with predominantly cognitive behavioral stress management content (StressProffen-cognitive behavioral therapy intervention [StressProffen-CBI]) and another with predominantly mindfulness-based stress management content (StressProffen-mindfulness-based intervention [StressProffen-MBI]).
View Article and Find Full Text PDFEngineering Under-Coordinated Active Sites with Tailored Chemical Microenvironments over Mosaic Bismuth Nanosheets for Selective CO Electroreduction to Formate.
Small
April 2023
State Key Laboratory Breeding Base of Green-Chemical Synthesis Technology, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, 310014, P. R. China.
Selective electrochemical reduction of CO into fuels or chemical feedstocks is a promising avenue to achieve carbon-neutral goal, but its development is severely limited by the lack of highly efficient electrocatalysts. Herein, cation-exchange strategy is combined with electrochemical self-reconstruction strategy to successfully develop diethylenetriamine-functionalized mosaic Bi nanosheets (mBi-DETA NSs) for selective electrocatalytic CO reduction to formate, delivering a superior formate Faradaic efficiency of 96.87% at a low potential of -0.
View Article and Find Full Text PDFMulticomponent Staff Training Intervention to Improve Residential Dementia Care (PROCUIDA-Demencia): A Mixed-Methods 2-Arm Cluster Randomized Controlled Pilot and Clinical Outcomes Study.
J Am Med Dir Assoc
March 2022
Department of Clinical Psychology, School of Health in Social Science, University of Edinburgh, Edinburgh, United Kingdom; Adult Mental Health Team Psychological Services, NHS Lothian, Royal Edinburgh Hospital, Edinburgh, United Kingdom.
Objectives: To evaluate the feasibility outcomes of implementing a multicomponent staff training intervention (PROCUIDA-Demencia) to promote psychosocial interventions and reduce antipsychotic prescription in Mexican care homes and study its effect on staff's care experience and residents' quality of life.
Design: A mixed-methods 2-arm cluster randomized controlled pilot study of a 2-day staff training program with baseline, 12 weeks, and 24 weeks of the PROCUIDA-Demencia intervention vs treatment as usual (TAU).
Setting And Participants: Eight care homes in Mexico City were selected, from which 55 residents and 126 staff were recruited.
MAUI (MBI Analysis User Interface)-An image processing pipeline for Multiplexed Mass Based Imaging.
PLoS Comput Biol
April 2021
School of Medicine, Department of Pathology, Stanford University, Stanford, California, United States of America.
Mass Based Imaging (MBI) technologies such as Multiplexed Ion Beam Imaging by time of flight (MIBI-TOF) and Imaging Mass Cytometry (IMC) allow for the simultaneous measurement of the expression levels of 40 or more proteins in biological tissue, providing insight into cellular phenotypes and organization in situ. Imaging artifacts, resulting from the sample, assay or instrumentation complicate downstream analyses and require correction by domain experts. Here, we present MBI Analysis User Interface (MAUI), a series of graphical user interfaces that facilitate this data pre-processing, including the removal of channel crosstalk, noise and antibody aggregates.
View Article and Find Full Text PDFMolecular Breast Imaging in Patients with Suspicious Calcifications.
J Breast Imaging
December 2019
Mayo Clinic, Department of Medicine, Rochester, MN.
Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m sestamibi) in the breast-in patients with suspicious calcifications on mammography.
Methods: Women scheduled for stereotactic biopsy of calcifications detected on 2D digital mammography were prospectively enrolled to undergo MBI before biopsy. Molecular breast imaging was performed with injection of Tc-99m sestamibi and a dual-detector, cadmium zinc telluride gamma camera.
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