Pheochromocytoma is a rare tumor that produces a distant effect by secretion of catecholamines. This tumor usually presents with hypertension and palpitations but it may also cause cardiogenic shock because of catecholamine-induced myocardial dysfunction. We describe a rare case of Takotsubo-like cardiomyopathy as first manifestation of pheochromocytoma with an unusual onset characterized by severe hypotension and transient basal left ventricular ballooning ('inverted' Takotsubo-like cardiomyopathy).
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Complex Presentation of Pheochromocytoma: Hypertensive Encephalopathy and Takotsubo-Like Cardiomyopathy in a Young Female.
Am J Case Rep
September 2024
Division of Cardiothoracic Surgery, Mayo Clinic, Jacksonville, FL, USA.
Article Synopsis
- Pheochromocytoma is a rare tumor that secretes catecholamines and can cause severe symptoms like high blood pressure, rapid heart rate, headaches, and sweating; timely diagnosis is crucial to prevent complications.
- A case study of a 25-year-old woman showed she presented with hypertensive encephalopathy and acute coronary syndrome linked to pheochromocytoma, which was later confirmed via imaging and biochemical tests.
- After targeted treatment and surgery to remove the tumor, the patient’s hypertension and symptoms fully resolved, underscoring the need to consider pheochromocytoma in cases of acute neurological and cardiac issues.
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Background: Adrenaline-producing tumors are mostly characterized by a sudden release of catecholamines with episodic symptoms. Noradrenergic ones are usually less symptomatic and characterized by a continuous overproduction of catecholamines that are released into the bloodstream. Their effects on the cardiovascular system can thus be different.
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